摘要
目的 探究数字乳腺断层摄影技术(DBT)对早期乳腺癌患者的诊断效能并与磁共振检查技术(MRI)进行比较。方法 回顾性分析2023年1—12月在江苏省肿瘤医院诊断为早期乳腺癌的50例患者资料,所有患者在接受病理学检查前均接受了影像学检查且影像学资料清晰完整。以病理学检查结果作为金标准,比较不同影像检查技术的检出准确率、灵敏度、特异度,并对比乳腺癌类型的分型结果与病理诊断结果。结果 DBT诊断乳腺病变的漏诊率、误诊率和准确率分别为4.00%(2/50)、6.00%(3/50)和90.00%(45/50),与MRI比较[2.00%(1/50)、4.00%(2/50)、94.00%(47/50)]差异均无统计学意义;以病理检查结果为金标准进行比较,DBT对乳腺癌类型的诊断结果差异无统计学意义;50例早期乳腺癌患者中共发现87处肿块(恶性54处,良性33处),DBT诊断的灵敏度和阴性预测值低于MRI,但特异度和阳性预测值高于MRI,且两者准确率相当;DBT和MRI的成本效益比(CER)分别为3.25和12.17,以DBT为基准,MRI的增量成本效益比(ICER)为713.91。结论 数字乳腺断层摄影技术诊断乳腺癌患者的准确率和效益均较高,值得推广。
Objective To investigate the diagnostic efficacy of digital breast tomosynthesis(DBT)in detecting early-stage breast cancer and compare its efficacy with that of magnetic resonance imaging(MRI).Methods A retrospective analysis was conducted on 50 patients diagnosed with early-stage breast cancer between January 2023 and December 2023.All patients underwent imaging examination,with complete and high-quality imaging data prior to pathological examination.The pathological findings were used as the gold standard to compare detection accuracy,sensitivity,and specificity DBT and MRI,as well as breast cancer staging consistency between imaging and pathology.Results The rates of missed diagnoses,misdiagnosis,and accuracy in detecting breast lesions for DBT were 4.00%(2/50),6.00%(3/50),and 90.00%(45/50),respectively.Compared with MRI[2.00%(1/50),4.00%(2/50),and 94.00%(47/50)],these differences were not statistically significant.Based on the pathological examination results as the gold standard,there was no statistically significant difference in the diagnostic results of DBT for breast cancer type classification.A total of 87 breast masses(54 malignant and 33 benign)were identified in 50 patients with early-stage breast cancer.DBT demonstrated lower diagnostic sensitivity and negative predictive value than MRI,it exhibited higher specificity and positive predictive value.Overall diagnostic accuracy was comparable between the two modalities.The cost-benefit ratio(CER)for DBT and MRI were 3.25 and 12.17,respectively,and the incremental cost-benefit ratio(ICER)for MRI relative to DBT was 713.91.Conclusion Digital breast tomosynthesis offers high accuracy and favorable cost-effectiveness in the diagnosis of patients with breast cancer,making it a valuable tool worthy of broader clinical application.
作者
杨燕
赵玉年
茅昌飞
唐晓雯
李冬雪
YANG Yan;ZHAO Yunian;MAO Changfei;TANG Xiaowen;LI Dongxue(Department of Radiology,Jiangsu Cancer Hospital,Jiangsu Institute of Cancer Research,the Affiliated Cancer Hospital of Nanjing Medical University,Nanjing,Jiangsu 210000,China)
出处
《中华全科医学》
2025年第6期1004-1007,共4页
Chinese Journal of General Practice
基金
国家自然科学基金项目(82204524)。
