摘要
目的探究低出生体重儿甲状腺功能与宫外生长发育的关系。方法选取低出生体重儿98例,根据甲状腺功能是否异常分为正常组(54例)和甲减组(44例)。比较两组住院期间临床资料及宫外生长发育情况。采用Logistic回归分析甲状腺功能与宫外生长发育的关系。结果甲减组胎龄、出生体质量低于正常组,合并宫内生长发育迟缓占比高于正常组(P<0.05)。甲减组体质量增长速度低于正常组,肠内营养持续时间、完全经口喂养时间高于正常组(P<0.05)。肠内营养持续时间、完全经口喂养时间是LBWI出现甲状腺功能异常的危险因素(P<0.05)。结论低出生体重儿甲状腺功能与宫外生长发育存在一定的关联,临床应尽早干预。
Aim To explore the relationship between thyroid function and extrauterine growth in low-birth-weight infants.Methods A total of 98 low-birth-weight infants were selected and divided into the normal group(54 cases)and the hypothyroidism group(44 cases)according to whether the thyroid function was abnormal.The clinical data during hospitalization and the extrauterine growth and development of the two groups were compared.Logistic regression was used to analyze the relationship between thyroid function and extrauterine growth and development.Results The gestational age and birth weight of the hypothyroidism group were lower than those of the normal group,and the proportion of combined intrauterine growth retardation was higher than that of the normal group(P<0.05).The weight gain rate of the hypothyroidism group was lower than that of the normal group,and the duration of enteral nutrition and the time of full oral feeding were higher than those of the normal group(P<0.05).The duration of enteral nutrition and the time of full oral feeding were risk factors for abnormal thyroid function in low-birth-weight infants(P<0.05).Conclusion There is a certain correlation between thyroid function and extrauterine growth in low-birth-weight infants,and clinical intervention should be carried out as early as possible.
作者
薛丹
陈佳
XUE Dan;CHEN Jia(Department of Neonatology,Mianyang Central Hospital,Affiliated Mianyang Hospital,School of Medicine,University of Electronic Science and Technology of China,Mianyang 621000,Sichuan,China)
出处
《中南医学科学杂志》
2025年第4期637-639,734,共4页
Medical Science Journal of Central South China
基金
四川省卫生和计划生育委员会科研课题(18PJ048)。
