摘要
目的:运用Meta分析评价针灸疗法治疗肿瘤相关性抑郁(Cancer-related Depression,CRD)患者的临床疗效。方法:在数据库中检索2019年1月―2023年11月关于针灸治疗CRD的随机对照试验(Randomized Controlled Trial,RCT)研究,按照纳排标准对文献进行剔选,并提取相关信息进行系统评价和质量分析。结果:共检索371篇文献,其中15篇文献符合要求。结果显示:针灸治疗CRD总有效率高于常规治疗[比值比(OR)=2.79,95%置信区间(CI)(1.99,3.90),P<0.00001]。针灸疗法能降低CRD患者的汉密尔顿抑郁量表(Hamilton Depression Rating Scale,HAMD)评分[均方差(MD)=–3.76,95%CI(–5.39,–2.12),P<0.00001]和抑郁自评量表(Self-rating Depression Scale,SDS)评分[MD=–4.41,95%CI(–8.61,–0.20),P<0.04],并能提高癌症患者生活质量问卷核心30条目(Quality of Life Questionnaire for Cancer Patients-Core 30,QLQ-30)评分[MD=11.35,95%CI(6.83,15.87),P<0.00001]。结论:研究表明,针灸在改善CRD患者的抑郁状态方面有良好的临床疗效。
Objective:To evaluate the clinical efficacy of acupuncture and moxibustion in the treatment of cancer-related depression(CRD)by Meta-analysis.Methods:Randomized controlled trials(RCTs)on acupuncture and moxibustion in the treatment of CRD from January 2019 to November 2019 were searched in the databases,literatures were selected according to the inclusion and exclusion criteria,and relevant information was extracted for systematic evaluation and quality analysis.Results:A total of 371 articles were retrieved,15 of which met the requirements.The results showed that the effective rate of acupuncture and moxibustion on CRD was higher than that of conventional treatment[Odds Ratio(OR)=2.79,95%CI(1.99,3.90),P<0.00001].Acupuncture and moxibustion therapy could reduce the HAMD score[mean difference(MD)=–3.76,95%CI(–5.39,–2.12),P<0.00001]and self-rating depression scale(SDS)score in CRD patients[MD=–4.41,95%CI(–8.61,–0.20),P<0.04],also improved the QLQ-30 score of patients[MD=11.35,95%CI(6.83,15.87),P<0.00001].Conclusion:Studies have shown that acupuncture and moxibustion has good clinical efficacy in ameliorating the depressive state in patients with CRD.
作者
曾书莹
徐鑫鑫
武富平
何筱明
林可萌
余志红
ZENG Shuying;XU Xinxin;WU Fuping;HE Youmeng;LIN Keming;YU Zhihong
出处
《中医临床研究》
2025年第6期1-6,共6页
Clinical Journal Of Chinese Medicine
基金
2021年浙江省国医名师传承工作室建设项目(GZS2021001)。
关键词
针灸
肿瘤相关性抑郁
META分析
穴位
Acupuncture and moxibustion
Cancer-related depression
Meta-analysis
Acupoint
