摘要
目的了解帕金森(Parkinson′s disease,PD)患者睡眠情况,并探讨其与运动障碍、不良情绪的关系。方法选取成都市第三人民医院2022年9月至2024年5月收治的满足纳排标准的308例PD患者为研究对象,分析其睡眠情况[匹兹堡睡眠质量指数(PSQI)]、运动障碍[简化Fugl-Meyer运动功能评定量表(FMA)]及不良情绪[贝克焦虑问卷(BAI)、贝克抑郁问卷(BDI-Ⅱ)]得分,并对比不同人口学特征患者PSQI得分,用P earson相关性分析帕金森患者睡眠与运动障碍及不良情绪的相关性。结果308例患者PSQI量表总分(6.16±0.97)分,其中208例(67.53%)伴有睡眠障碍。睡眠障碍组中女性、61~75岁、中专及以下、病程4年及以上、Hoehn-Yahr分期Ⅳ期、未婚占比均高于无睡眠障碍组(P<0.05)。与无睡眠障碍组比,睡眠障碍组FMA评分较低(P<0.05),BAI、BDI-Ⅱ得分较高(P<0.05)。Pearson相关性分析结果显示,PSQI与FMA呈负相关(r=-0.489,P<0.05),PSQI与BAI、BDI-Ⅱ均呈正相关(r=0.476、0.502,P<0.05)。结论PD患者睡眠障碍发生率较高,PSQI与FMA呈负相关PSQI与BAI、BDI-Ⅱ均呈正相关。
Objective To understand the sleep status in patients with Parkinson′s disease(PD),and to explore its relationship with dyskinesia and negative emotions.Methods A total of 308 patients with PD who met the inclusion and exclusion criteria in the hospital from September 2022 to May 2024 were selected as the research subjects.The scores of sleep status[Pittsburgh Sleep Quality Index(PSQI)],dyskinesia[Simplified Fugl-Meyer Motor Assessment(FMA)]and negative emotions[Beck Anxiety Inventory(BAI),Beck Depression Inventory-Ⅱ(BDI-Ⅱ)]were analyzed,and the PSQI score was compared among patients with different demographic characteristics.Pearson correlation analysis was performed to analyze the correlation of sleep with dyskinesia and negative emotions in patients with PD.Results The total score of PSQI scale was(6.16±0.97)points in 308 PD patients,of which 208 cases(67.53%)were complicated with sleep disorders.The proportions of female,61-75 years old,technical secondary school or below,disease course of 4 years and above,Hoehn-Yahr stage Ⅳ and unmarried status in the sleep disorder group were higher than those in the non-sleep disorder group(P<0.05).Compared with the non-sleep disorder group,the FMA score in the sleep disorder group was lower(P<0.05)while the BAI score and BDI-Ⅱ score were higher(P<0.05).Pearson correlation analysis revealed that PSQI was negatively correlated with FMA(r=-0.489,P<0.05),and was positively correlated with BAI and BDI-Ⅱ(r=0.476,0.502,P<0.05).Conclusion The incidence rate of sleep disorders in PD patients is high.PSQI is negatively correlated with FMA,and is positively correlated with BAI and BDI-Ⅱ.
作者
吴敏
钟靓
林姮
杨熙
WU Min;ZHONG Liang;LIN Heng;YANG Xi(Department of Neurology,The Third People′s Hospital of Chengdu,Chengdu,Sichuan 610031,China)
出处
《公共卫生与预防医学》
2025年第4期51-54,共4页
Journal of Public Health and Preventive Medicine
基金
四川省卫生健康委员会科研项目(19PJ010)。
关键词
帕金森
睡眠
运动障碍
不良情绪
相关性
Parkinson′s disease
Sleep
Dyskinesia
Negative emotions
Correlation
