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奥赛利定与氢吗啡酮用于腹腔镜全子宫切除术后镇痛的效果观察

Observation of Effect of Oliceridine and Hydromorphone on Postoperative Analgesia after Laparoscopic Total Hysterectomy
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摘要 目的:探讨奥赛利定与氢吗啡酮用于腹腔镜全子宫切除术后镇痛的效果。方法:回顾性选取2024年5—9月宁德市闽东医院收治的81例行腹腔镜子宫全切术患者作为研究对象,根据不同麻醉方案分为对照组41例与试验组40例。对照组在常规麻醉基础上加用氢吗啡酮,试验组在常规麻醉基础上加用奥赛利定,比较两组术后不同时间镇痛效果[视觉模拟评分法(VAS)评分]、镇痛泵按压次数、首次下床时间、首次排气时间、术后镇痛满意度及术后不良反应。结果:两组术后不同时间VAS评分与镇痛泵按压次数比较,差异无统计学意义(P>0.05);试验组首次下床时间、首次排气时间早于对照组,术后镇痛满意度评分高于对照组,术后不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论:腹腔镜全子宫切除术患者给予奥赛利定能提供良好的术后镇痛,减少不良反应。 Objective:To investigate the effect of Oliceridine and Hydromorphone on postoperative analgesia after laparoscopic total hysterectomy.Method:A total of 81 patients underwent laparoscopic total hysterectomy who admitted to Ningde Mindong Hospital from May to September 2024 were retrospectively selected as the study subjects,and they were divided into the control group(n=41)and the experimental group(n=40)according to the different anesthesia schemes.The control group was treated with Hydromorphone on the basis of conventional anesthesia,and the experimental group was treated with Oseltadine on the basis of conventional anesthesia.The analgesic effect[visual analogue scale(VAS)score],the number of times of pressing the analgesic pump,the first time of getting out of bed,the first time of exhaust,the satisfaction of postoperative analgesia and postoperative adverse reactions were compared between two groups.Result:There were no significant differences in VAS scores and analgesic pump pressing times between two groups at different time after operation(P>0.05);the first time to get out of bed and the first time to exhaust in the experimental group were earlier than those in the control group,the postoperative analgesia satisfaction score was higher than that in the control group,and the incidence of postoperative adverse reactions was lower than that in the control group,the differences were statistically significant(P<0.05).Conclusion:Oselidine can provide good postoperative analgesia and reduce adverse reactions in patients undergoing laparoscopic total hysterectomy.
作者 刘恒 陈飞 黄庆清 LIU Heng;CHEN Fei;HUANG Qingqing(Ningde Mindong Hospital,Fu’an 355000,China;不详)
机构地区 宁德市闽东医院
出处 《中外医学研究》 2025年第17期138-141,共4页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 腹腔镜 子宫切除术 奥赛利定 氢吗啡酮 Laparoscopy Hysterectomy Oliceridine Hydromorphone
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