摘要
抑制宿主核转录因子-κB(NF-κB)信号通路活性、降低乳腺组织活性氧积聚是缓解反刍奶畜乳腺炎的可行方案。花青素是植物体内重要的次级代谢产物,不仅具有较高的自由基清除能力,且具有极强的抗炎症作用,是预防反刍奶畜乳腺炎的高效绿色添加剂。基于此,本文主要综述了反刍动物常见饲料中花青素含量、NF-κB在乳腺炎中的作用机制及花青素介导NF-κB信号通路缓解反刍奶畜乳腺炎的作用机制,旨在为预防反刍奶畜乳腺炎提供科学依据,对绿色畜牧业的发展也有重要作用。
The inhibition of nuclear factor-kappa B(NF-κB)signaling pathway and reactive oxygen species are the key and feasible ways to solve mastitis of dairy ruminants.Anthocyanins are important secondary metabolites of plants which can not only enhance the free radical scavenging ability,but also have a strong anti-inflammatory effect.Thus,anthocyanins can recognize as the most potential green additive for prevention of mastitis of dairy ruminants.For this reason,this paper mainly reviews the anthocyanin content in common feeds of ruminants,the mechanism of NF-κB in mastitis,and the mechanism of anthocyanins reduce mastitis by suppressing NF-κB signaling pathway in dairy ruminants.This review can provide a scientific basis for the prevention of mastitis in dairy ruminants.
作者
卢琦
周迪
班超
田兴舟
LU Qi;ZHOU Di;BAN Chao;TIAN Xingzhou(Key Laboratory of Animal Genetics,Breeding and Reproduction in the Plateau Mountainous Region,Ministry of Education,Guizhou University,Guiyang 550025,China;College of Animal Science,Guizhou University,Guiyang 550025,China;Guizhou Testing Center for Livestock and Poultry Germplasm,Guiyang 550018,China;School of Animal Technology and Innovation,Suranaree University of Technology,Nakhon Ratchasima 30000,Thailand)
出处
《动物营养学报》
北大核心
2025年第6期3510-3518,共9页
CHINESE JOURNAL OF ANIMAL NUTRITION
基金
国家自然科学基金项目(32302779,32260849)
贵州省科技计划项目(黔科合支撑[2022]重点033)
贵州省基础研究计划(自然科学)青年引导项目(黔科合基础-[2024]青年106)
贵州省教育厅高等学校自然科学研究项目(黔教技[2024]33号)
贵州大学基础研究项目(贵大基础[2023]16号)。
关键词
花青素
抗炎性
乳腺炎
反刍奶畜
anthocyanins
anti-inflammatory
mastitis
dairy ruminant
