摘要
目的:分析高频重复经颅磁刺激(rTMS)联合利培酮治疗酒精所致精神障碍的效果。方法:选取2021年4月—2023年4月临沭县精神卫生中心收治的94例酒精所致精神障碍患者为研究对象,根据抽签法进行分组,研究组、对照组均为47例。对照组采用利培酮治疗,研究组在对照组基础上实施rTMS。比较两组治疗效果。结果:治疗后,两组阴性症状评分、阳性症状评分及总分低于治疗前(P<0.05),且研究组低于对照组(P<0.001)。治疗后,两组简易精神状态评价量表评分升高(P<0.05),且研究组高于对照组(P<0.001)。治疗后,两组生理、心理、社会、环境评分升高,且研究组高于对照组(P<0.05)。研究组不良反应总发生率低于对照组(P=0.025)。结论:rTMS联合利培酮治疗酒精所致精神障碍的效果显著,可缓解患者精神症状,改善认知功能,提高生活质量,降低不良反应发生率。
Objective:To analyze the efficacy of high-frequency repetitive transcranial magnetic stimulation(rTMS)combined with risperidone in the treatment of alcohol-induced mental disorders.Methods:A total of 94 patients with alcohol-induced mental disorders admitted to the Mental Health Center of Linshu County from April 2021 to April 2023 were selected as the study subjects.They were divided into two groups(47 patients each)by the lottery method:the study group and the control group.The control group received risperidone treatment,while the study group was treated with rTMS in addition to risperidone.The therapeutic effects of the two groups were compared.Results:After treatment,the negative symptom scores,positive symptom scores,and total scores of both groups were lower than before treatment(P<0.05),with the study group showing lower scores than the control group(P<0.001).After treatment,the Mini-Mental State Examination(MMSE)scores of both groups increased(P<0.05),with the study group scoring higher than the control group(P<0.001).After treatment,the physiological,psychological,social,and environmental scores of both groups improved,and the study group had higher scores than the control group(P<0.05).The total incidence of adverse reactions in the study group was lower than that in the control group(P=0.025).Conclusion:The combination of rTMS and risperidone demonstrates significant efficacy in treating alcohol-induced mental disorders.It can alleviate psychiatric symptoms,improve cognitive function,enhance quality of life,and reduce the incidence of adverse reactions.
作者
王通收
张艳华
Wang Tongshou;Zhang Yanhua(Department of Psychiatry,Linshu County Mental Health Center,Linyi 276700,Shandong Province,China)
出处
《中国社区医师》
2025年第15期49-51,共3页
Chinese Community Doctors
关键词
酒精所致精神障碍
高频重复经颅磁刺激
利培酮
Alcohol-induced psychotic disorder
High-frequency repetitive transcranial magnetic stimulation
Risperidone
