摘要
骨质疏松症是一种以骨脆性增强为主要表现的全身性骨病,中医学将其归为“骨痹”“骨痿”等范畴。杜仲作为防治骨质疏松症的常用中药,具有补肝益肾,强壮筋骨之功效。该文简要回顾了关于杜仲的相关研究,重点介绍了杜仲治疗骨质疏松症的作用机制,发现杜仲主要通过激活间充质干细胞及成骨细胞分化信号通路、促进骨形成等方式改善骨质疏松。
Osteoporosis is a kind of systemic bone disease mainly manifested by the enhancement of bone fragility,which is classified as the category of"bone bi"and"bone flaccidity"in the field of traditional Chinese medicine.As a common Chinese medicine for the prevention and treatment of osteoporosis,Eucommia ulmoides has the effect of nourishing the liver and kidney and strengthening the muscles and bones.This article briefly reviews the researches regarding Eucommia ulmoides,focuses on the introduction of the mechanism of action of Eucommia ulmoides in treatment of osteoporosis,reveals that Eucommia ulmoides can improve osteoporosis by activating the differentiation signaling pathways of mesenchymal stem cells and osteoblasts and promoting bone formation.
作者
郭亦
Guo Yi(Nanjing University of Chinese Medicine,Nanjing 213000,Jiangsu Province,China)
出处
《中国社区医师》
2025年第15期1-3,共3页
Chinese Community Doctors
关键词
杜仲
骨质疏松症
骨髓间充质干细胞
成骨细胞
Eucommia ulmoides
Osteoporosis
Bone mesenchymal stem cells
Osteoblasts