摘要
据统计,全世界近10%的成年人患糖尿病,维生素D水平降低可能与2型糖尿病及其并发症的发病风险相关。目前临床研究发现,补充维生素D可能对胰岛素敏感性及血糖水平存在改善作用,使得维生素D补充作为一种潜在干预策略备受关注。未来需开展更高质量、大规模的临床试验,以验证维生素D的干预效果,并明确其在糖代谢异常的预防与治疗中的相关机制,为个体化医学提供可靠依据。
Approximately 10%of the global adult population has diabetes,with accumulating evidence linking suboptimal vitamin D levels to an increased risk of type 2 diabetes and its complications.Current clinical studies suggest that vitamin D supplementation may enhance insulin sensitivity and improve glycemic control,prompting significant interest in its potential as a therapeutic intervention.However,further high-quality,large-scale randomized controlled trials are required to validate its efficacy in glucose metabolism regulation and clarify the underlying molecular mechanisms.These investigations will provide critical evidence to inform precision medicine approaches for diabetes prevention and management.
作者
陈胤
张芝田
刘娇娇
颜红梅
郭珊珊
CHEN Yin;ZHANG Zhitian;LIU Jiaojiao;YAN Hongmei;GUO Shanshan(Department of Endocrinology and Metabolism,Zhongshan Hospital,Fudan University,Shanghai 200032,China;School of Sports and Health,Shanghai University of Sport,Shanghai 200438,China)
出处
《中国临床医学》
2025年第3期512-518,共7页
Chinese Journal of Clinical Medicine
关键词
糖代谢异常
维生素D
临床研究
glucose metabolism disorder
vitamin D
clinical research
