摘要
癫痫是一种神经系统疾病,以神经元异常同步放电导致的反复发作性脑功能障碍为特征。癫痫患者通常合并各种睡眠障碍,如不宁腿综合征/周期性肢体运动障碍、失眠症和发作性睡病。频繁的癫痫发作可能会增加罹患睡眠障碍的风险;反之,睡眠障碍控制不佳会加重癫痫。本文通过阐述癫痫患者常见的睡眠障碍类型,揭示可能的发病机制,并介绍癫痫与睡眠障碍共病的治疗新进展,旨在说明癫痫和睡眠障碍之间的相互作用,为临床上更有效地治疗睡眠障碍、改善癫痫患者的预后提供了新的思路与经验。
Epilepsy,which leads to an enduring high tendency to generate epileptic seizures,is a neurological disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to abnormal synchronous neuronal discharges.Patients with epilepsy are usually comorbid with various sleep disorders,such as restless leg syndrome/periodic limb movement disorder(RLS/PLMD),chronic insomnia and narcolepsy.Frequent seizures may increase the risk of suffering from sleep disorders;conversely,poor control of sleep disorders exacerbates epilepsy.This review discusses common types of sleep disorders in patients with epilepsy,reveals potential mechanisms,and introduces new advances in the treatment of comorbidity between epilepsy and sleep disorders.The aim is to provide an overview of the close interactions between epilepsy and sleep disorders,providing new ideas and experiences for more effective treatment of sleep disorders and improving the prognosis of patients with epilepsy.
作者
黄路遥
丁晶
汪昕
HUANG Luyao;DING Jing;WANG Xin(Department of Neurology,Zhongshan Hospital,Fudan University,Shanghai 200032,China)
出处
《中国临床医学》
2025年第3期505-511,共7页
Chinese Journal of Clinical Medicine
基金
国家重点研发计划(2022YFC2503802)。
