摘要
目的 探讨肝动脉灌注化疗(HAIC)对Ⅱ-Ⅲ期肝癌疗效的预测价值。方法 选取2021年11月至2024年3月在南昌市第九医院行3次及以上HAICⅡ-Ⅲ期的肝癌患者81例。通过CT或MRI比较患者每个治疗周期后肿瘤局部反应,根据mRECIST标准,对患者第1、2次及最后1次HAIC的疗效进行比较分析,评估HAIC对Ⅱ-Ⅲ期肝癌早期疗效的预测价值。结果 第1次与最后1次HAIC后疗效对比,67例患者疗效相同或相近,14例患者疗效相异,疗效预测率达82.72%;第2次与最后1次HAIC后疗效对比,71例患者疗效相同或相近,10例患者疗效相异,疗效预测率达87.65%。结论 HAICⅡ-Ⅲ期肝癌的早期疗效可以对其完成总疗程的最终疗效起预测指导作用。
Objective To discuss the prediction value of the early efficacy of hepatic arterial infusion chemotherapy(HAIC)in treating stage II-II hepatocellular carcinoma(HCC).Methods The clinical data of 81 patients with stage II-II HCC,who received at least 3 times of HAIC at the Nanchang Municipal Central Hospital of China from November 2021 to March 2024,were retrospectively analyzed.CT or MRI was used to compare patient's local tumor response after each treatment cycle.Based on modified Response Evaluation Criteria in Solid Tumors(mRECIST),the curative effects of patients after receiving the first,the second,and the last HAIC treatment were compared between each other.The prediction value of the early efficacy of HAIC in treating patients with stage II-II HCC was analyzed.Results In the 67 patients,the efficacy of the last time HAIC was equal or similar to that of the first time HAIC,and in the remaining 14 patients the efficacy of the last time HAIC was different from that of the first time HAIC,with an efficacy prediction rate of 82.72%.The efficacy of the last time HAIC was equal or similar to that of the second time HAIC in 71 patients,and in the remaining 10 patients the efficacy of the last time HAIC was different from that of the second time HAIC,with an efficacy prediction rate of 87.65%.Conclusion In treating stage II-II HCC with HAIC,the early efficacy can be used to predict the final efficacy after completion of the total treatment course.
作者
杨文娟
吴美儿
张克勤
余海滨
刘金明
欧阳兵
王文英
魏玲
熊述
YANG Wenjuan;WU Meier;ZHANG Keqin;YU Haibin;LIU Jinming;OUYANG Bing;WANG Wenying;WEI Ling;XIONG Shu(Department of Liver Oncology,Nanchang Municipal Ninth Hospital,Nanchang,Jiangxi Province 330000,China)
出处
《介入放射学杂志》
北大核心
2025年第5期493-495,共3页
Journal of Interventional Radiology
基金
南昌市医疗卫生引导性科技计划项目(2023YLWS046)。
关键词
肝动脉灌注化疗
Ⅱ-Ⅲ期肝癌
早期疗效
hepatic arterial infusion chemotherapy
stage II-Il hepatocellular carcinoma
early efficacy
