摘要
目的了解3种过碳酸钠消毒剂的理化特性、对指示菌的消毒效果及其对常见金属的腐蚀性。方法测定A、B和C 3种过碳酸钠消毒剂的活性氧含量、pH值及对不锈钢、碳钢、铝和铜的腐蚀性,采用悬液定量杀菌试验评估其对指示菌的杀菌效果。结果A、B和C消毒剂的活性氧含量分别为13.2%、12.1%和8.93%,其中A、B消毒剂符合标准规定,C消毒剂低于标准要求。在活性氧含量1.0%时,A、B和C消毒剂的pH值分别为10.23、10.10和10.52,均符合标准范围。3种消毒剂对不锈钢、铝、铜无明显腐蚀性,但对碳钢有轻微腐蚀。在杀菌试验中,B消毒剂的杀菌效果优于A和C,其中A与C的杀菌性能相当。B消毒剂在0.05%活性氧含量下对大肠埃希菌作用30 min、在0.1%活性氧含量下对铜绿假单胞菌作用30 min、在0.6%活性氧含量下对金黄色葡萄球菌作用15 min,杀灭对数值均≥5.00;A、C消毒剂需延长作用时间至45 min方能达到消毒合格要求。在对白念珠菌的杀菌试验中,3种消毒剂在2.0%活性氧含量作用15 min,杀灭对数值均≥4.00;其中B消毒剂可在15 min内完全杀灭白念珠菌,而A、C消毒剂需延长至30 min才能实现完全杀灭。在枯草杆菌黑色变种芽孢杀灭试验中,3种消毒剂在3.0%活性氧含量作用120 min后,杀灭对数值均≤5.00,未达到消毒合格要求。结论3种过碳酸钠消毒剂对细菌繁殖体和真菌的杀灭作用较强,但对芽孢的杀灭能力较弱,对碳钢有轻度腐蚀。
Objective To investigate the physicochemical properties,disinfection efficacy against indicator microorganisms,and corrosion effects on common metals of three sodium percarbonate-based disinfectants.Methods The active oxygen content,pH value and metal corrosiveness of the three sodium percarbonate disinfectants were measured.Their bactericidal efficacy was evaluated using the quantitative suspension test.Results The active oxygen content of disinfectant A,B and C were 13.2%,12.1% and 8.93%,respectively.A and B met the standard requirements,while C fell below the standard.At active oxygen content of 1.0%,the pH values of A,B,and C were 10.23,10.10,and 10.52.All three disinfectants showed no significant corrosiveness to stainless steel,aluminum,or copper,but exhibited slight corrosiveness to carbon steel.The killing log value(KL)against Escherichia coli of disinfectant B≥5.00 with 0.05% active oxygen content incubating for 30 min,against Pseudomonas aeruginosa needed 0.1% active oxygen content for 30 min,and against Staphylococcus aureus needed 0.6% active oxygen content for 15 min.Disinfectant A and C needed 45 min to reach KL≥5.00.For Candida albicans,all three disinfectants with 2.0% active oxygen content achieved KL≥4.00 after 15 min.B completely eliminated Candida albicans within 15 min,while samples A and C required 30 min for complete eradication.In the test against Bacillus subtilis var.niger,all three disinfectants at 3.0% active oxygen content failed to reach KL≤5.00 after 120 min.Conclusion All three sodium percarbonate disinfectants can effectively killing bacterial propagules and fungi,but showed limited efficacy against spores and exhibited slight corrosiveness to carbon steel.
作者
房琼琼
王劲
肖潇
高迪
佟颖
于礼
FANG Qiong-qiong;WANG Jin;XIAO Xiao;GAO Di;TONG Ying;YU Li(Beijing Center for Disease Control and Prevention,Beijing 100013,China)
出处
《中国消毒学杂志》
2025年第5期325-328,共4页
Chinese Journal of Disinfection
基金
高层次公共卫生技术人才建设项目(学科带头人-01-15,学科骨干-02-16)。
关键词
过碳酸钠消毒剂
理化特性
杀菌效果
sodium percarbonate disinfectant
physicochemical properties
germicidal efficacy
