摘要
目的观察齐刺电针治疗痰瘀阻络型股骨头坏死的临床疗效及对骨代谢的影响。方法将80例痰瘀阻络型股骨头坏死患者随机分为治疗组和对照组,每组40例。对照组采用口服股骨头坏死愈胶囊治疗,治疗组在对照组基础上予齐刺电针治疗。观察两组治疗前后中医证候积分、Harris髋关节功能评分、疼痛视觉模拟量表(visual analog scale,VAS)评分以及血清骨代谢相关因子Ⅰ型前胶原N端前肽(bone metabolism related factor type Ⅰ procollagen N-terminal peptide,PINP)和β胶原降解产物(βcollagen degradation products,β-CTX)水平的变化,比较两组临床疗效。结果治疗组总有效率高于对照组,差异有统计学意义(P<0.05)。两组治疗后Harris评分、血清PINP水平均较治疗前升高(P<0.05),VAS评分、中医证候积分以及血清β-CTX水平均较治疗前降低(P<0.05)。治疗组治疗后Harris评分和血清PINP水平高于对照组(P<0.05),VAS评分、中医证候积分和血清β-CTX水平低于对照组(P<0.05)。结论在口服股骨头坏死愈胶囊基础上,齐刺电针治疗痰瘀阻络型股骨头坏死能有效减轻疼痛,改善髋关节功能及临床症状,提高疗效,对骨代谢相关因子也有明显调节作用。
Objective To observe the clinical efficacy of triple needling plus electroacupuncture in treating femoral head necrosis(FHN)with phlegm-stasis obstruction pattern and its effect on bone metabolism.Method Eighty patients were randomly divided into a treatment group and a control group,with 40 cases in each group.The control group received oral Gu Gu Tou Huai Si Yu capsules,while the treatment group received additional triple needling plus electroacupuncture.Traditional Chinese medicine(TCM)syndrome scores,Harris hip scores,visual analog scale(VAS)scores,and serum bone metabolism related factor type Ⅰ procollagen N-terminal peptide(PINP)and βcollagen degradation products(β-CTX)were compared before and after treatment.The clinical efficacy was evaluated between the two groups.Result The total effective rate in the treatment group was significantly higher than that in the control group(P<0.05).After treatment,both groups showed increased Harris hip scores and serum PINP levels(P<0.05),as well as decreased VAS scores,TCM syndrome scores,and serum β-CTX levels(P<0.05).The treatment group exhibited higher Harris hip scores and serum PINP levels(P<0.05)and lower VAS scores,TCM syndrome scores,and serum β-CTX levels(P<0.05)compared to the control group.Conclusion Surrounding electroacupuncture combined with oral Gu Gu Tou Huai Si Yu capsules can effectively alleviate pain,improve hip joint function and clinical symptoms,and regulate bone metabolism in FHN patients with phlegm-stasis obstruction pattern.
作者
张宇
阎晓霞
ZHANG Yu;YAN Xiaoxia(Henan University of Chinese Medicine,Zhengzhou 450046,China;Henan Provincial Orthopedic Hospital,Zhengzhou 450016,China)
出处
《上海针灸杂志》
2025年第6期711-715,共5页
Shanghai Journal of Acupuncture and Moxibustion
基金
国家中医临床研究基地科研专项(2022ZYZD13)
河南省中医药科学研究专项课题(2024ZY2115,20-21ZY1026)
河南省科技攻关项目(232102310423)。
关键词
针刺疗法
齐刺
电针
股骨头坏死
痰瘀阻络
骨代谢
Acupuncture therapy
Triple needling
Electroacupuncture
Femoral head necrosis
Phlegm-stasis obstruction
Bone metabolism
