摘要
目的:对急性下肢深静脉血栓(DVT)采用经皮人工血栓抽吸术(MAT)联合导管接触性溶栓术(CDT)治疗的效果进行研究。方法:选取2021年1月至2023年12月信阳市中心医院收治的84例急性DVT患者作为研究对象,按不同的手术干预方法分为对照组和观察组,其中41例患者单独接受CDT治疗作为对照组,另外43例患者接受MAT联合CDT治疗作为观察组,将两组患者介入手术时间、尿激酶总剂量、溶栓持续时间、手术费用、并发症、3个月时Villalta评分、血栓清除效果、静脉通畅评分、患-健肢周径差等临床围手术期指标和疗效指标进行对比。结果:观察组患者介入手术所需时间长于对照组,但尿激酶总剂量、溶栓持续时间、3个月时Villalta评分明显低于对照组(P<0.05),两组患者在手术费用、并发症比较上无明显差异(P>0.05)。治疗前两组患者在静脉通畅评分、患-健肢周径之差方面比较无明显差异(P>0.05),治疗后观察组静脉通畅评分和患-健肢周径之差均小于对照组(P<0.05),进一步比较两组患者静脉通畅程度、患肢消肿程度,观察组效果明显优于对照组(P<0.05)。结论:MAT与CDT联合使用是一种治疗急性DVT的有效、安全和经济的介入手术方法。
Objective To investigate the efficacy of percutaneous manual aspiration thrombectomy(MAT)combined with catheter-directed thrombolysis(CDT)in the treatment of acute lower extremity deep venous thrombosis(DVT).Methods:84 patients with acute DVT from Central Hospital of Xinyang were enrolled and divided into control and observation groups based on different surgical interventions.The control group(n=41)received CDT alone,while the observation group(n=43)underwent MAT combined with CDT.Clinical perioperative and efficacy indicators,including interventional procedure duration,total urokinase dose,thrombolysis duration,surgical costs,complications,Villalta score at 3 months,thrombus clearance effect,venous patency score and circumference difference between affected and healthy limbs,were compared between the two groups.Results:The observation group had a longer interventional procedure duration than the control group,but significantly lower total urokinase dose,thrombolysis duration and Villalta score at 3 months(P<0.05).No significant differences were observed in surgical costs and complications between the two groups(P>0.05).Before treatment,there were no significant differences in venous patency score and circumference difference between affected and healthy limbs between the two groups(P>0.05).After treatment,both venous patency score and circumference difference were significantly lower in the observation group than in the control group(P<0.05).Further comparison of venous patency and limb swelling reduction revealed significantly better outcomes in the observation group than in the control group(P<0.05).Conclusion:Combined use of MAT and CDT is an effective,safe and economical interventional method for the treatment of acute DVT.
作者
熊臣
杜鲲
贾萌
唐启耀
尹君
XIONG Chen;DU Kun;JIA Meng;TANG Qiyao;YIN Jun(Department of Interventional Radiology/Vascular Surgery,Central Hospital of Xinyang,Xinyang 464000,China)
出处
《黑龙江医药科学》
2025年第6期67-70,共4页
Heilongjiang Medicine and Pharmacy
基金
信阳市市级软科学研究项目,编号:20210031。
关键词
下肢深静脉血栓形成
经皮人工血栓抽吸
导管接触性溶栓
lower extremity deep venous thrombosis
percutaneous manual aspiration thrombectomy
catheter-directed thrombolysis
