摘要
BACKGROUND Hepatic perivascular epithelioid cell tumor(PEComa)is an extremely rare neo-plasm that is often difficult to diagnose due to its nonspecific clinical and radio-logical features.This case emphasizes the importance of imaging and histopatho-logical examination in distinguishing PEComa from other liver tumors,and the necessity of early intervention.CASE SUMMARY A 36-year-old woman presented with a liver mass discovered during a routine physical examination.Initially diagnosed as focal nodular hyperplasia based on contrast-enhanced computed tomography,she declined surgical intervention.Two years later,re-examination revealed an approximately 60%increase in the size of the mass and suggested the possibility of hepatocellular carcinoma.She subsequently underwent surgical resection.Postoperative histopathological and immunohistochemical analysis revealed positivity for HMB-45 and Melan-A,confirming the diagnosis of hepatic PEComa.A 13-month follow-up revealed no recurrence or metastasis.CONCLUSION Hepatic PEComa requires a combination of radiological and immunohistoche-mical evaluation for accurate diagnosis.This case highlights the importance of early surgical intervention and regular follow-up to monitor for recurrence or metastasis.
基金
Supported by National Natural Science Foundation of China,No.U22A2039.
