摘要
膀胱小细胞癌(small cell carcinoma of the bladder, SCCB)是一种快速进展的高度恶性罕见疾病,其生物学行为与肺小细胞癌高度相似。目前SCCB仍缺乏统一规范的标准治疗方案,现有研究多以个案报道形式呈现,临床治疗策略多参照肺小细胞癌及膀胱尿路上皮癌的治疗指南,治疗效果尚不理想。为梳理SCCB治疗研究现状,本研究以“small cell carcinoma of the bladder”为核心关键词,全面检索PubMed等数据库,对近年来有关SCCB的论著、综述及个案分析类文献进行系统分析,旨在整合当前诊疗方案,探索规范化治疗路径,为临床实践提供科学依据,提升临床获益。
Objective Methods Results Conclusions Small cell carcinoma of the bladder(SCCB)is a rare and rapidly progressing malignant disease,with biological behavior highly similar to small cell lung cancer.Currently,there is no standardized treatment regimen for SCCB,and most existing research is presented in the form of case reports.Clinical treatment strategies often refer to the treatment guidelines for small cell lung cancer and urothelial carcinoma of the bladder,but the therapeutic outcomes are still unsatisfactory.In order to summarize the current research on the treatment of SCCB,this study uses"small cell carcinoma of the bladder"as the core keyword and comprehensively searches PubMed and other databases.Then,a systematic analysis of recent articles,reviews,and case studies on SCCB is conducted,with the aim of integrating current diagnostic and treatment strategies,exploring a standardized treatment pathway,and providing scientific evidence for clinical practice to improve clinical outcomes.
作者
徐特
陈洪川
左明顺
廖远键
朱永攀
张能
XU Te;CHEN Hongchuan;ZUO Mingshun;LIAO Yuanjian;ZHU Yongpan;ZHANG Neng*(Department of Urology,the Affiliated Hospital of Zunyi Medical University,Zunyi,Guizhou 563000,China)
出处
《徐州医科大学学报》
2025年第5期375-379,共5页
Journal of Xuzhou Medical University
基金
国家自然科学基金(81860524)。
关键词
膀胱小细胞癌
神经内分泌肿瘤
治疗
免疫
根治性膀胱切除术
small cell carcinoma of the bladder
neuroendocrine neoplasm
treatment
immunity
radical cystectomy
