摘要
目的目的分析感染预警机制的多维管控干预体系对原发性肾病综合征患儿干预的效果。方法方法本研究纳入2022年6月-2024年3月期间于我院确诊并接受系统治疗的原发性肾病综合征病例101例,依据护理干预方案差异进行分组,其中观察组51例实施基于感染预警机制的多维管控干预,对照组50例采用常规护理。比较两组干预前以及干预后的炎症因子指标、24小时尿蛋白、用药依从性、生活质量、感染并发症发生率。结果结果干预后观察组患者C反应蛋白(hs-CRP)、白细胞介素6(IL-6)、24小时尿蛋白显著低于对照组(P<0.05);干预2、4、6个月观察组Morisky服药依从性量表评分均高于对照组(P<0.05);两组生活质量ISLQ评分高于干预前,且观察组高于对照组(P<0.05);干预后观察组并发症发生率为3.92%,低于对照组的20.00%(P<0.05)。结论结论通过信息、感染预警流程、环境、生活、心理多维度对肾病综合征患儿实施感染预警机制的多维管控干预,可有效降低患儿炎症水平、提高用药依从性和生活质量,并降低了患儿感染并发症的发生率。
Objective To analyze the effectiveness of a multidimensional control intervention system for infection warning mechanisms in intervening in children with primary nephrotic syndrome.Methods This study included 101 cases of primary nephrotic syndrome diagnosed and treated systematically in our hospital from June 2022 to March 2024.The patients were grouped based on the differences in the nursing intervention plans.Among them,51 cases in the observation group received multi-dimensional management intervention with an infection early warning mechanism,while 50 cases in the control group received conventional care.Compare the inflammatory cytokine indicators,24-hour urine protein,medication adherence,quality of life,and infection incidence between two groups before and after intervention.Results After intervention,the levels of C-reactive protein(hs-CRP),interleukin-6(IL-6),and 24-hour urinary protein in the observation group were significantly lower than those in the control group(P<0.05);the Morisky Medication Adherence Scale scores of the intervention groups at 2,4,and 6 months were higher than those of the control group(P<0.05);the ISLQ scores of both groups were significantly higher than before the intervention,and the observation group was higher than the control group(P<0.05);the incidence of complications in the observation group after intervention was 3.92%,which was lower than the 20.00%in the control group(P<0.05).Conclusion Implementing a multidimensional control intervention of infection warning mechanism for children with nephrotic syndrome through information,infection warning process,environment,life,and psychology can effectively reduce inflammation levels,improve medication compliance and quality of life,and reduce the incidence of infection complications in children.
作者
王盼盼
代婷婷
Wang Panpan;Dai Tingting(Xinjiang Hospital of Beijing Children’s Hospital,Pediatric Research Institute of Xinjang Uygur Autonomous Region,Children’s Hospital of Xinjang Uygur Autonomous Region,The Seventh People’s Hospital of Xinjiang Uygur Autonomous Region,Urumqi,Xinjiang 830000,China)
出处
《首都食品与医药》
2025年第12期131-134,共4页
Capital Food Medicine
关键词
原发性肾病综合征
多维管控干预
感染预警机制
炎症因子
用药依从性
并发症
primary nephrotic syndrome
Multidimensional control intervention
Infection warning mechanism
Inflammatory factors
Medication adherence
complication
