摘要
目的目的研究实验室精液检验对男性不育的诊断价值以及不同年龄下男性精液异常率。方法方法选择我院在2020年10月-2024年10月期间接收的2583例男性不育患者,患者在检查前需要保持2-7d的禁欲,通过手淫法获取精液,收集精液后,将其放置在清洁盖的小杯中,通过彩色精子质量检测系统对精子活力、精子密度等指标进行检验,统计各个年龄段男性人群的精液异常率。结果结果精液正常患者有770例,精液异常患者有1813例,两组患者的精液量、pH值对比,差异无统计学意义(P>0.05),精液正常组精液液化时间少于异常组,精液正常组精子数、精子总活力、前向运动力高于异常组,差异有统计学意义(P<0.05);精液异常组患者中精液异常率最高的指标为精子总活力,占比为23.22%(421/1813),其次为前向运动力,占比为20.08%(364/1813),再次为液化时间,占比为17.37%(315/1813);无精子症患者去除后,将精液异常患者根据年龄分为4个阶段,分别为≤20岁、21-30岁、31-40岁、>40岁,>40岁的患者前向运动力占比、精液浓度、精子总活力低于其他三个年龄段患者,且表现为相对降低趋势,精液量、pH值、精子正常形态率对比,差异无统计学意义(P>0.05);>40岁患者的精液异常率高于≤20岁、31-40岁、21-30岁患者。结论结论在男性不育诊断中,应用实验室精液检验,可发现男性不育患者的精子活力相对较差,且和年龄具有一定关系,特别是年龄超过40岁的男性精子异常率相对较高。
Objective To investigate the diagnostic value of laboratory semen testing for male infertility and the abnormal rate of male semen at different ages.Methods A total of 2583 male infertility patients admitted to our hospital from October 2020 to October 2024 were selected.Patients were required to maintain abstinence for 2-7 days before examination,and their semen was obtained through masturbation.After collecting the semen,it was placed in a small cup with a clean lid.The sperm motility,sperm density,and other indicators were tested using a color sperm quality detection system,and the abnormal rate of semen in male populations of different ages was statistically analyzed.Results There were 770 patients with normal semen and 1813 patients with abnormal semen.There was no statistically significant difference in semen volume and pH value between the two groups of patients(P>0.05).The liquefaction time of semen in the normal semen group was shorter than that in the abnormal group,while the number of sperm,total sperm motility,and forward motility in the normal semen group were higher than those in the abnormal group,and the difference was statistically significant(P<0.05);the highest indicator of semen abnormality rate in patients with semen abnormalities is total sperm motility,accounting for 23.22%(421/1813),followed by forward motility,accounting for 20.08%(364/1813),and liquefaction time,accounting for 17.37%(315/1813);after removing patients with azoospermia,patients with abnormal semen were divided into four stages based on age:≤20 years old,21-30 years old,31-40 years old,and>40 years old.Patients over 40 years old had lower proportions of forward motility,semen concentration,and total sperm motility compared to the other three age groups,and showed a relative decreasing trend,in semen volume,pH value and the normal morphology rate of sperm there was no statistically significant difference(P>0.05).The abnormal rate of semen in patients aged 40 is higher than that in patients aged≤20,31-40,and 21-30.Conclusion In the diagnosis of male infertility,laboratory semen testing can reveal that the sperm motility of male infertility patients is relatively poor and is related to age,especially in males over 40 years old where the rate of abnormal sperm is relatively high.
作者
李文峰
聂林
黄素丽
孟子飘
王小岚
Li Wenfeng;Nie Lin;Huang Suli;Meng Zipiao;Wang Xiaolan(Xiaogan Maternal and Child Health Hospital,Xiaogan,Hubei 432100,China)
出处
《首都食品与医药》
2025年第12期46-49,共4页
Capital Food Medicine
基金
孝感市自然科学计划项目(编号:XGKJ2023010033)。
