摘要
目的调查中晚期肺腺癌化疗患者抑郁情绪现状及影响因素。方法选择本院2020年1月~2023年5月中晚期肺腺癌化疗患者196例作为研究对象,采用抑郁自评量表评估患者抑郁状态,同时比较不同婚姻状态、化疗认知度、年龄、工作情况、家庭月收入情况、居住地、文化程度、医疗费用支付方式的评估结果,采用多因素logistic回归分析中晚期肺腺癌化疗患者抑郁情绪的影响因素。结果本研究中196例中晚期肺腺癌化疗患者存在抑郁情绪者173例(88.27%),无抑郁情绪者23例(11.73%);不同年龄的中晚期肺腺癌化疗患者抑郁情况比较,差异无统计学意义(P>0.05);不同婚姻状态、化疗认知度、工作情况、家庭月收入情况、居住地、文化程度、医疗费用支付方式的中晚期肺腺癌化疗患者抑郁情况比较,差异有统计学意义(P<0.05);采用多因素logistic回归分析结果显示,婚姻状态、化疗认知度、工作情况、家庭月收入情况、居住地、文化程度、医疗费用支付方式均为中晚期肺腺癌化疗患者抑郁状态的影响因素(P<0.05)。结论中晚期肺腺癌化疗患者抑郁情绪发生率较高,其影响因素包括婚姻状态、化疗认知度、工作情况、家庭月收入情况、居住地、文化程度、医疗费用支付方式等多个方面,今后临床可针对患者抑郁具体影响因素做出针对性调控措施。
Objective To study and analyze the depressive emotional state and its influencing factors in advanced pulmonary adenocarcinoma patients with chemotherapy.Method A total of 196 patients with mid-advanced lung adenocarcinoma receiving chemotherapy from January 2020 to May 2023 were selected as the study objects.The depression status of patients was assessed by self-rating depression scale.Meanwhile,the evaluation results of different marital status,chemotherapy awareness,age,job status,family monthly income,residence,education level and payment method of medical expenses were compared.Multivariate logistic regression was used to analyze the influencing factors of depressive emotional state in patients with advanced lung adenocarcinoma treated with chemotherapy.Results In this study,173(88.27%)of the 196 patients with advanced lung adenocarcinoma undergoing chemotherapy had depression,while 23(11.73%)had no depression.There was no statistically significant difference(P>0.05)in the incidence of depression among patients with advanced lung adenocarcinoma undergoing chemotherapy in different ages.There was statistically significant difference in depression among patients with advanced lung adenocarcinoma undergoing chemotherapy,including different marital status,chemotherapy awareness,work status,monthly family income,place of residence,educational level,and payment methods for medical expenses(P<0.05).The results of multivariate logistic regression analysis showed that marital status,chemotherapy awareness,work status,monthly family income,place of residence,education level,and medical expense payment method were all influencing factors for depression in patientswith advanced lung adenocarcinoma undergoing chemotherapy,and the difference was statistically significant(P<0.05). Conclusion The incidence of depression in patients with mid to late stage lung adenocarcinoma undergoingchemotherapy is relatively high. The influencing factors include marital status,chemotherapy awareness,work status,monthly family income,residence,education level,and payment methods for medical expenses. In the future,targetedcontrol measures can be taken in clinical practice to address the specific influencing factors of depression in patients.
作者
王冬冬
刘俏
闫小龙
WANG Dongdong;LIU Qiao;YAN Xiaolong(The Second Affiliated Hospital of the Chinese People's Liberation Army Air Force Military Medical University,Xi'an 710038,China)
出处
《国际精神病学杂志》
2025年第2期642-645,共4页
Journal Of International Psychiatry
基金
国家自然科学基金项目(编号:81873820)。
关键词
抑郁
中晚期肺腺癌
化疗
情绪
Depression
Middle to late stage lung adenocarcinoma
Chemotherapy
Emotion
