摘要
目的探究罗哌卡因复合地佐辛应用于分娩镇痛硬膜外麻醉中对产妇疼痛程度的影响。方法120例分娩产妇,以双色球法分为对照组与研究组,各60例。对照组分娩镇痛硬膜外麻醉中使用罗哌卡因,研究组分娩镇痛硬膜外麻醉中采用罗哌卡因复合地佐辛。对比两组产妇的疼痛程度、新生儿Apgar评分、不良妊娠结局发生情况、产程时间。结果研究组产妇麻醉后5 min(T0)、麻醉后10 min(T1)、麻醉后15 min(T2)以及麻醉后20 min(T3)时视觉模拟评分法(VAS)评分分别为(5.31±0.27)、(4.30±0.35)、(3.21±0.26)、(1.84±0.26)分,均显著低于对照组的(6.28±0.24)、(5.13±0.24)、(4.17±0.33)、(3.24±0.27)分,统计学组间差异明显(P<0.05)。研究组新生儿出生后1、5、10 min Apgar评分分别为(9.03±1.07)、(9.45±1.21)、(9.87±0.56)分,显著高于对照组的(8.46±1.11)、(9.02±1.13)、(9.67±0.33)分,统计学组间差异明显(P<0.05)。研究组产妇不良妊娠结局发生率10.00%低于对照组的26.67%,统计学组间差异明显(P<0.05)。研究组顺产产妇第一产程时间(218.22±43.87)min、第二产程时间(17.36±3.28)min、第三产程时间(9.02±1.17)min、总产程时间(244.60±45.44)min均短于对照组的(256.17±55.98)、(21.50±3.22)、(10.49±2.32)、(288.16±50.15)min,统计学组间差异明显(P<0.05)。结论在分娩镇痛硬膜外麻醉中使用罗哌卡因复合地佐辛能够有效缓解产妇疼痛,缩短分娩时间,提升新生儿健康水平,降低不良妊娠结局发生风险。
Objective To explore the effect of epidural anesthesia with ropivacaine and dezocine for labor analgesia on maternal pain severity.Methods 120 cases of parturient women were divided into control group and study group with two-color ball method,each with 60 cases.The control group used epidural anesthesia with ropivacaine for labor analgesia,and the study group used epidural anesthesia with dezocine for labor analgesia.The pain severity,neonatal quality,adverse pregnancy outcome and labor duration of the two groups were compared.Results 5 min after anesthesia(T0),10 min after anesthesia(T1),15 min after anesthesia(T2),and 20 min after anesthesia(T3),VAS scores of the study group were(5.31±0.27),(4.30±0.35),(3.21±0.26),and(1.84±0.26)points,which were significantly lower than(6.28±0.24),(5.13±0.24),(4.17±0.33),and(3.24±0.27)points in the control group,and the difference was statistically significant(P<0.05).Apgar scores at 1,5 and 10 min after birth were(9.03±1.07),(9.45±1.21)and(9.87±0.56)points in the study group,which were significantly higher than(8.46±1.11),(9.02±1.13)and(9.67±0.33)points in the control group,and the statistical difference was significant(P<0.05).The incidence of adverse pregnancy outcome in the study group was 10.00%,which was lower than 26.67%in the control group,and the difference was statistically significant(P<0.05).In the study group,the first stage of labor was(218.22±43.87)min,the second stage of labor was(17.36±3.28)min,the third stage of labor was(9.02±1.17)min,and the total duration of labor was(244.60±45.44)min,which were shorter than(256.17±55.98),(21.50±3.22),(10.49±2.32),and(288.16±50.15)min in the control group,and the difference was statistically significant(P<0.05).Conclusion In epidural anesthesia for labor analgesia,the combination of ropivacaine and dexmedetomidine can effectively alleviate maternal pain,shorten delivery time,improve neonatal health,and reduce the risk of adverse pregnancy outcomes.
作者
张传朋
ZHANG Chuan-peng(Second Department of Anesthesiology,Weifang Hospital of Traditional Chinese Medicine,Weifang 261000,China)
出处
《中国现代药物应用》
2025年第11期24-28,共5页
Chinese Journal of Modern Drug Application
关键词
罗哌卡因
地佐辛
分娩
硬膜外麻醉
镇痛
Ropivacaine
Dezocine
Delivery
Epidural anesthesia
Analgesia
