摘要
目的分析子宫肌瘤治疗中腹腔镜下子宫肌瘤剥除术的临床效果。方法60例子宫肌瘤患者,依据手术方法的不同分为腹腔镜手术组(腹腔镜下子宫肌瘤剥除术)和开腹手术组(开腹子宫肌瘤剥除术),各30例。比较两组围手术期指标、性激素[黄体生成素(LH)、抗苗勒氏管激素(AMH)、卵泡刺激素(FSH)、雌二醇(E_(2))]水平、心理状态[汉密尔顿焦虑量表(HAMA)和汉密尔顿抑郁量表(HAMD)评分]、生活质量[肿瘤患者生活质量评分(QOL)]、性生活质量[女性性功能指数量表(FSFI)评分]、术后并发症发生情况及疗效。结果腹腔镜手术组患者的术中出血量(99.43±9.56)ml少于开腹手术组的(139.56±9.21)ml,手术时间(109.65±9.12)min、肛门排气时间(14.75±0.35)h、术后镇痛时间(2.75±1.63)d、术后住院时间(4.21±0.66)d短于开腹手术组的(121.52±9.23)min、(22.23±0.56)h、(3.74±1.36)d、(6.86±1.32)d(P<0.05)。腹腔镜手术组患者的总有效率96.67%(29/30)高于开腹手术组的73.33%(22/30)(χ^(2)=6.405,P<0.05)。手术后,两组患者的血清LH、FSH水平及QOL评分、FSFI均高于手术前,AMH、E_(2)水平及HAMA评分、HAMD均低于手术前(P<0.05);且腹腔镜手术组患者的血清LH、FSH水平及HAMA评分、HAMD均低于开腹手术组,AMH、E_(2)水平及QOL、FSFI评分均高于开腹手术组(P<0.05)。腹腔镜手术组患者的术后并发症发生率10.00%(3/30)低于开腹手术组的33.33%(10/30)(χ^(2)=4.812,P<0.05)。结论子宫肌瘤患者实施腹腔镜下子宫肌瘤剥除术的临床效果较开腹子宫肌瘤剥除术好。
Objective To analyze the clinical effect of laparoscopic myomectomy in the treatment of uterine fibroids.Methods According to different surgical methods,60 patients with uterine fibroids were divided into laparoscopic surgery group(laparoscopic myomectomy)and open surgery group(open myomectomy),with 30 cases in each group.Patients in both groups were compared in terms of perioperative indexes,levels of sex hormone[luteinizing hormone(LH),anti-Muller's hormone(AMH),follicle-stimulating hormone(FSH),estradiol(E2)],psychological state[Hamilton Anxiety Scale(HAMA)and Hamilton Depression Scale(HAMD)scores],quality of life(QOL),sexual life quality[Female Sexual Function Index Scale(FSFI)score],incidence of postoperative complications and efficacy.Results In laparoscopic surgery group,the intraoperative blood loss was(99.43±9.56)ml,which was less than(139.56±9.21)ml in open surgery group;the operation time was(109.65±9.12)min,the anal exhaust time was(14.75±0.35)h,the postoperative analgesia time was(2.75±1.63)d,and the postoperative hospitalization time was(4.21±0.66)d,which were shorter than(121.52±9.23)min,(22.23±0.56)h,(3.74±1.36)d,and(6.86±1.32)d in open surgery group(P<0.05).The total effective rate in laparoscopic surgery group was 96.67%(29/30),which was higher than 73.33%(22/30)in open surgery group(χ^(2)=6.405,P<0.05).After operation,the serum LH,FSH levels,QOL score and FSFI score in both groups were higher than those before operation,and AMH,E2 levels,HAMA score and HAMD score were lower than those before operation(P<0.05).The serum LH and FSH levels,HAMA score and HAMD score in laparoscopic surgery group were lower than those in open surgery group,and AMH,E2 level,QOL score and FSFI scores were higher than those in open surgery group(P<0.05).The incidence of postoperative complications in laparoscopic surgery group was 10.00%(3/30),which was lower than 33.33%(10/30)in open surgery group(χ^(2)=4.812,P<0.05).Conclusion The clinical effect of laparoscopic myomectomy in patients with uterine fibroids is better than that of open myomectomy.
作者
杜媛媛
DU Yuan-yuan(Department of Gynecology,Chifeng Municipal Hospital,Chifeng 024000,China)
出处
《中国实用医药》
2025年第10期72-75,共4页
China Practical Medicine
