摘要
目的分析老年缓慢性心律失常患者应用双腔心脏起搏器治疗的临床效果。方法选取老年缓慢性心律失常患者72例作为研究对象,并按照双色球法将患者分为对照组和研究组,每组36例。对照组采用单腔心脏起搏器治疗,研究组采用双腔心脏起搏器治疗。对比两组的心功能指标、血生化指标、不适症状积分、认知功能评分。结果治疗后,研究组左心室射血分数、左心室舒张末期内径、每搏输出量、心输出量、心脏指数、心率均优于对照组,存在统计学意义(P<0.05)。治疗后,研究组血小板聚集率为(36.31±4.68)%、全血粘度为(6.69±0.46)mPa·s、血浆粘度为(1.60±0.18)mPa·s、肌酸激酶同工酶为(13.40±4.09)IU/L、血清肌钙蛋白I为(0.017±0.006)ng/ml,对照组血小板聚集率为(39.86±5.22)%、全血粘度为(7.37±0.53)mPa·s、血浆粘度为(1.79±0.16)mPa·s、肌酸激酶同工酶为(18.40±4.24)IU/L、血清肌钙蛋白I为(0.027±0.007)ng/ml。两组血生化指标对比,存在统计学意义(P<0.05)。治疗后,研究组气短乏力症状积分为(3.28±1.70)分,头晕症状积分为(1.13±0.40)分,心悸症状积分为(2.68±0.17)分,胸痛症状积分为(7.20±1.93)分;对照组气短乏力症状积分为(5.66±1.15)分,头晕症状积分为(1.88±0.31)分,心悸症状积分为(1.85±0.40)分,胸痛症状积分为(10.14±1.41)分。两组不适症状积分对比,存在统计学意义(P<0.05)。治疗后,研究组蒙特利尔认知评估量表(MoCA量表)评分为(25.47±1.31)分、简易智力状态检查量表(MMSE)评分为(26.90±1.39)分;对照组MoCA量表评分为(21.44±1.19)分、MMSE评分为(21.43±1.21)分。两组认知功能评分对比,存在统计学意义(P<0.05)。结论老年缓慢性心律失常患者应用双腔心脏起搏器治疗的临床效果显著,值得推广利用。
Objective To analyze the clinical effect of dual-chamber pacemaker treatment for elderly patients with bradyarrhythmia.Methods 72 elderly patients with bradyarrhythmia were selected as the study subjects,and divided into control group and study group using the bicolor sphere method,with 36 cases in each group.The control group was treated with single-chamber pacemaker,while the study group was treated with dual-chamber pacemaker.Comparison of the cardiac function,blood biochemical indicators,discomfort symptom scores,and cognitive function between the two groups.Results After treatment,the left ventricular ejection fraction,left ventricular end-diastolic diameter,stroke output,cardiac output,cardiac index and heart rate in the study group were better than those in the control group,and there was statistical significance(P<0.05).After treatment,the platelet aggregation rate in the study group was(36.31±4.68)%,the whole blood viscosity was(6.69±0.46)mPa·s,the plasma viscosity was(1.60±0.18)mPa·s,the creatine kinase isoenzyme was(13.40±4.09)IU/L,and the serum troponin I was(0.017±0.006)ng/ml;in the control group,the platelet aggregation rate was(39.86±5.22)%,the whole blood viscosity was(7.37±0.53)mPa·s,the plasma viscosity was(1.79±0.16)mPa·s,the creatine kinase isoenzyme was(18.40±4.24)IU/L and the serum troponin I was(0.027±0.007)ng/ml.There was no statistical significance in blood biochemical indicators between the two groups(P<0.05).After treatment,the shortness of breath and fatigue symptom score in the study group was(3.28±1.70)points,the dizziness symptom score was(1.13±0.40)points,the palpitation symptom score was(2.68±0.17)points,and the chest pain symptom score was(7.20±1.93)points;in the control group,the shortness of breath and fatigue symptom score was(5.66±1.15)points,the dizziness symptom score was(1.88±0.31)points,the palpitation symptom score was(1.85±0.40)points and the chest pain symptom score was(10.14±1.41)points.There was statistically significance in comparison of discomfort symptom scores between the two groups(P<0.05).After treatment,the Montreal cognitive assessment scale(MoCA)score in the study group was(25.47±1.31)points,and the mini-mental state examination(MMSE)score was(26.90±1.39)points;in the control group,the MoCA score was(21.44±1.19)points,and the MMSE score was(21.43±1.21)points.There was statistical significance in cognitive function scores between the two groups(P<0.05).Conclusion The clinical effect of dual-chamber pacemakers in elderly patients with bradyarrhythmia is significant,and is worthy of promotion and utilization.
作者
李凤翔
孙宇
LI Feng-xiang;SUN Yu(Heilongjiang Mudanjiang Medical College Affiliated Hongqi Hospital,Mudanjiang 157011,China)
出处
《中国实用医药》
2025年第10期46-49,共4页
China Practical Medicine
