摘要
目的 探讨骨折早期肢体肿胀患者运用中药贴敷联合桃红四物汤加减治疗对患者疼痛情况、血流动力学指标、中医证候积分及不良反应发生率的影响。方法 选取2023年6月至2024年4月于简阳市中医医院就诊的骨折早期肢体肿胀患者200例,随机分为对照组与观察组,各100例。对照组予以甘露醇注射液治疗,观察组采用中药贴敷联合桃红四物汤加减治疗,比较两组患者的治疗效果。结果 治疗后观察组视觉模拟评分法(VAS)评分低于对照组(P<0.05);治疗后观察组全血高切黏度、全血低切黏度、血浆黏度低于对照组(P<0.05);治疗后观察组肿胀、疼痛、瘀血评分低于对照组(P<0.05);观察组不良反应发生率低于对照组(P<0.05);观察组疼痛时长、骨痂形成时间、骨折端愈合时间、患肢恢复负重时间短于对照组(P<0.05);观察组治疗后36条简明健康状况调查量表(SF-36)、改良Barthel指数(MBI)评分高于对照组(P<0.05)。结论 对于骨折早期肢体肿胀患者,采用中药贴敷联合桃红四物汤加减治疗能够有效缓解临床症状、疼痛情况,改善血流动力学,用药安全性较高,加速康复,提高生命质量及生活自理能力。
Objective To explore the effects of traditional Chinese medicine application combined with modified Taohong Siwu Decoction on the pain status,hemodynamic indicators,TCM syndrome score and the incidence of adverse reactions in patients with early limb swelling in fractures.Methods Two hundred patients with early limb swelling due to fractures who visited Jianyang Hospital of Traditional Chinese Medicine from June 2023 to April 2024 were selected and randomly divided into a control group and an observation group,with 100 cases in each group.The control group was treated with mannitol injection,while the observation group was treated with traditional Chinese medicine patches combined with modified Taohong Siwu Decoction.The therapeutic effects of the two groups of patients were compared.Results After the treatment,the Visual Analogue Scale(VAS)score of the observation group was lower than that of the control group(P<0.05).After treatment,the high shear viscosity of whole blood,low shear viscosity of whole blood and plasma viscosity in the observation group were lower than those in the control group(P<0.05).After the treatment,the scores of swelling,pain and congestion in the observation group were lower than those in the control group(P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group(P<0.05).The duration of pain,the time of callus formation,the healing time of fracture ends,and the time for the affected limb to resume weight-bearing in the observation group were shorter than those in the control group(P<0.05).After treatment,the scores of the 36-item Short Form 36 Health Survey(SF-36)and the Modified Barthel Index(MBI)in the observation group were higher than those in the control group(P<0.05).Conclusion For patients with limb swelling in the early stage of fractures,the application of traditional Chinese medicine patches combined with modified Taohong Siwu Decoction can effectively alleviate clinical symptoms and pain,improve hemodynamics,have relatively high medication safety,accelerate recovery,and enhance the quality of life and self-care ability.
作者
郭太霞
李科
GUO Tai-Xia;LI Ke(Department of Pharmacy,Jianyang Hospital of Traditional Chinese Medicine,Chengdu 641400,China;Department of Orthopedics and Traumatology,Jianyang Hospital of Traditional Chinese Medicine,Chengdu 641400,China)
出处
《中国药物经济学》
2025年第4期100-103,共4页
China Journal of Pharmaceutical Economics
关键词
中药贴敷
桃红四物汤加减
骨折
早期肢体肿胀
疼痛
血流动力学
证候积分
不良反应
Traditional Chinese medicine application
Modified Taohong Siwu Decoction
Fracture
Early limb swelling
Pain
Hemodynamics
Syndrome score
Adverse reactions
