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体外膜肺氧合联合传统心肺复苏对心脏骤停患者心肌损伤及生命体征变化的影响

The Effect of Extracorporeal Membrane Oxygenation Combined with Traditional Cardiopulmonary Resuscitation on Myocardial Injury and Changes in Vital Signs in Patients with Cardiac Arrest
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摘要 目的:探讨体外膜肺氧合(ECMO)联合传统心肺复苏治疗心脏骤停的临床效果。方法:回顾性分析厦门大学附属中山医院2017年6月~2023年6月收治的70例心脏骤停患者临床资料,按治疗方法不同进行分组,将接受传统心肺复苏治疗的36例设为对照组,将接受ECMO治疗的34例设为观察组。比较两组抢救成功率、心肌损伤指标、生命体征及并发症。结果:观察组抢救成功率高于对照组(P<0.05);观察组治疗72h后肌酸激酶同工酶、乳酸脱氢酶、肌钙蛋白水平低于对照组(P<0.05);观察组心率、平均动脉压高于对照组(P<0.05);两组并发症相比无差异(P>0.05)。结论:ECMO联合传统心肺复苏可提高心脏骤停患者抢救成功率,加快生命体征复常,减轻心肌损伤,安全可行。 Objective:To investigate the clinical effect of extracorporeal membrane oxygenation(ECMO)combined with traditional cardiopulmonary resuscitation(CPR)in the treatment of cardiac arrest.Methods:The clinical data of 70 patients with cardiac arrest admitted to Zhongshan Hospital of Xiamen University from June 2017 to June 2023 were retrospectively analyzed.The patients were divided into different groups according to different treatment methods.36 cases receiving traditional cardiopulmonary resuscitation were set as control group,and 34 cases receiving ECMO were set as observation group.The rescue success rate,myocardial injury index,vital signs and complications were compared between the two groups.Results:The success rate of rescue in observation group was higher than that in control group(P<0.05).The levels of CK-MB,LDH and cTnI in observation group were lower than those in control group after 72h of treatment(P<0.05);HR and MAP in observation group were higher than those in control group(P<0.05).There was no difference in complications between the two groups(P>0.05).Conclusion:ECMO combined with traditional cardiopulmonary resuscitation can improve the rescue success rate of patients with cardiac arrest,accelerate the recovery of vital signs,reduce myocardial damage,and is safe and feasible.
作者 赖晓勤 李娟 刘慧恒 王隽笙 刘晓楣 LAI Xiao-qin;LI Juan;LIU Hui-heng;WANG Jun-sheng;LIU Xiao-mei(Emergency Department,Xiamen University Affiliated Zhongshan Hospital,Fujian Xiamen 361000)
出处 《中国医疗器械信息》 2025年第9期125-127,共3页 China Medical Device Information
关键词 心脏骤停 体外膜肺氧合 传统心肺复苏 心肌损伤 生命体征 cardiac arrest extracorporeal membrane oxygenation traditional cardiopulmonary resuscitation myocardial injury vital signs
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