摘要
目的:旨在评估基于CT血管成像(CTA)的颈动脉狭窄定量评估在预测卒中风险中的价值。方法:选取北京市中医医院顺义医院2019年1月~2022年4月的120例接受颈动脉CTA检查的患者。根据CTA图像,利用专用软件测量颈动脉狭窄的程度,并将患者分为轻度狭窄组34例(狭窄度<50%)、中度狭窄组46例(狭窄度50%~70%)和重度狭窄组40例(狭窄度>70%)。对所有患者进行为期两年的随访,记录卒中发生情况,并分析不同狭窄程度组的卒中发生率。采用Kaplan-Meier生存曲线分析不同狭窄程度组的卒中发生风险,并使用Cox回归模型调整其他可能的混杂因素。结果:随访期间,共发生卒中事件22例。其中,轻度狭窄组卒中发生率为14.71%,中度狭窄组为32.61%,重度狭窄组为75.00%。Kaplan-Meier曲线显示,重度狭窄组的卒中发生风险显著高于轻度和中度狭窄组(P<0.01)。Cox回归分析结果显示,颈动脉狭窄程度是卒中发生的重要独立预测因素(HR=1.85,95%CI:1.32~2.58,P<0.01)。结论:基于CTA的颈动脉狭窄定量评估能够有效预测卒中风险,且颈动脉狭窄程度与卒中发生风险呈正相关,重度狭窄患者的卒中风险显著增加。
Objective:This study aimed to evaluate the value of quantitative assessment of carotid artery stenosis based on CT angiography(CTA)in predicting stroke risk.Methods:120 patients who underwent carotid artery CTA examination in Shunyi Hospital,Beijing Traditional Chinese Medicine Hospital from January 2019 to April 2022 were selected.Based on the CTA images,special software was used to measure the degree of carotid artery stenosis,and the patients were divided into mild stenosis group(stenosis<50%)(n=34)and moderate stenosis group(stenosis 50%-70%)(n=46)and severe stenosis group(stenosis>70%)(n=40).All patients were followed up for two years,the occurrence of stroke was recorded,and the incidence of stroke in different stenosis degree groups was analyzed.Kaplan-Meier survival curves were used to analyze the risk of stroke in different stenosis degree groups,and Cox regression models were used to adjust for other possible confounding factors.Results:During the follow-up period,a total of 22 stroke events occurred.Among them,the incidence rate of stroke was 14.71%in the mild stenosis group,32.61%in the moderate stenosis group,and 75.00%in the severe stenosis group.The Kaplan-Meier curve showed that the risk of stroke in the severe stenosis group was significantly higher than that in the mild and moderate stenosis groups(P<0.01).Cox regression analysis results showed that the degree of carotid artery stenosis was an important independent predictor of stroke(HR=1.85,95%CI:1.32-2.58,P<0.01).Conclusion:Quantitative assessment of carotid artery stenosis based on CTA can effectively predict the risk of stroke,and the degree of carotid artery stenosis is positively correlated with the risk of stroke.The risk of stroke in patients with severe stenosis is significantly increased.
作者
马卫霞
张力
MA Wei-xia;ZHANG Li(Radiological Department Shunyi Hospital,Beijing Traditional Chinese Medicine Hospital,Beijing 101300)
出处
《中国医疗器械信息》
2025年第9期92-94,共3页
China Medical Device Information
关键词
CT血管成像
颈动脉狭窄定量
卒中风险
预测价值
CT angiography
quantification of carotid artery stenosis
stroke risk
predictive value
