摘要
中医药防治包括代谢相关脂肪性肝病(MAFLD)等的代谢性疾病效果显著。现从MAFLD的中医病名,病因病机,证候分型,体质辨识,中药汤药、中成药、非药物疗法等治疗手段,化痰祛瘀、养肝益肾、疏肝健脾、化湿清热等治则治法,中医动物模型、单味药及有效成分、复方等作用机制研究方面进行综述,以归纳总结中医药防治MAFLD的相关研究进展,为后续研究提供一定的借鉴和参考。
Traditional Chinese medicine(TCM) has demonstrated significant efficacy in the prevention and treatment of metabolic diseases,including metabolic-associated fatty liver disease(MAFLD).This review explores various aspects of TCM in the management of MAFLD,including its TCM nomenclature,etiology and pathogenesis,syndrome differentiation,and constitution classification.Additionally,it summarizes treatment approaches such as Chinese herbal decoctions,Chinese patent medicines,and non-pharmacological therapies.The therapeutic principles of resolving phlegm and removing stasis,nourishing the liver and kidney,soothing the liver and strengthening the spleen,and resolving dampness and clearing heat are discussed in detail.Furthermore,research progress in TCM-related MAFLD studies,including animal models,single herbs and active components,and compound formulas,is reviewed.This study aims to provide insights and references for future research on TCM-based MAFLD prevention and treatment.
作者
张潞潞
张建军
张秀平
方旖旎
董阳
王晓乾
张钧豪
张鹏
程引
王立英
李玲孺
ZHANG Lulu;ZHANG Jianjun;ZHANG Xiuping;FANG Yini;DONG Yang;WANG Xiaoqian;ZHANG Junhao;ZHANG Peng;CHENG Yin;WANG Liying;LI Lingru(Shanxi Key Laboratory of Chinese Medicine Encephalopathy,National International Joint Research Center for Molecular Chinese Medicine,Shanxi University of Chinese Medicine,Jinzhong 030619,China;Beijing University of Chinese Medicine Third Affiliated Hospital,Beijing 100029,China;National Institute of Traditional Chinese Medicine Constitution and Preventive Medicine,Beijing University of Chinese Medicine,Beijing 100029,China;Monitoring and Statistical Research Center,National Administration of Traditional Chinese Medicine,Beijing 100027,China;Institute of Basic Theory for Chinese Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China)
出处
《世界中医药》
北大核心
2025年第5期860-866,共7页
World Chinese Medicine
基金
国家自然科学基金面上项目(82374308)
国家重点研发计划项目(2022YFC2010104)
中央级公益性科研院所基本科研业务费专项资金资助项目(YZ-202157)
山西中医药大学博士科研启动基金资助项目(2024BK07)。
关键词
代谢相关脂肪性肝病
病名
病因病机
证型分型
体质辨识
治疗手段
治则治法
作用机制
Metabolism-associated fatty liver disease
Disease nomenclature
Etiology and pathogenesis
Syndrome differentiation
Constitution identification
Treatment methods
Treatment principles and methods
Mechanism of action
