摘要
目的观察利多卡因联合曲安奈德关节突封闭治疗在骨质疏松性椎体压缩骨折(OVCF)经皮椎体后凸成形术(PKP)中的临床效果。方法选取2021年9月—2024年2月在景德镇市第一人民医院收治的OVCF患者110例,采用随机数字表法分为观察组和对照组,各55例。对照组行PKP治疗,观察组采用PKP联合关节突封闭(盐酸利多卡因注射液+曲安奈德注射液)治疗。比较2组术后1周、术后1个月及术后6个月疼痛评分、功能障碍评分及骨折愈合情况(骨折椎体后凸Cobb角、椎体前缘高度)。结果2组术后1周、术后1个月及术后6个月疼痛评分均较术前降低,且观察组低于对照组(P<0.05或P<0.01);2组术后1周、术后1个月及术后6个月功能障碍评分均较术前降低,且观察组低于对照组(P<0.01);2组术后1周、术后1个月及术后6个月骨折椎体后凸Cobb角减小,伤椎前缘高度增高,且观察组减小/增高幅度大于对照组(P<0.01)。结论利多卡因联合曲安奈德关节突封闭治疗对OVCF患者PKP术后镇痛效果明显,可有效提高椎体矫正效果,且能改善伤椎功能。
Objective To observe the clinical effect of lidocaine combined with triamcinolone acetonide PKP of OVCF.Methods A total of 110 patients with OVCF who were admitted to the First People′s Hospital of Jingdezhen from September 2021 to February 2024 were selected and divided into observation group and control group,with 55 cases in each group.The control group was treated with PKP,and the observation group was treated with PKP combined with facet occlusion(lidocaine hydrochloride injection triamcinolone acetonide injection).The pain scores,functional impairment ratings,and fracture healing(kyphotic Cobb angle,anterior edge height,vertebral frontal height)were compared between the two groups at 1 week,1 month and 6 months after surgery.Results The pain scores of the two groups were lower at 1 week,1 month and 6 months after surgery than before operation,and the observation group was lower than that of the control group(P<0.05 or P<0.01).The functional impairment scores of the two groups at 1 week,1 month and 6 months after surgery were lower than those before operation,and those in the observation group were lower than those in the control group(P<0.01).The Cobb angle of the fractured vertebral kyphosis decreased 1 week,1 month after surgery,and 6 months after surgery in the two groups,and the height of the anterior edge of the injured vertebra increased,and the decrease/increase in the observation group was greater than that in the control group(P<0.01).Conclusion Lidocaine combined with triamcinolone acetonide articular process occlusion has a significant analgesic effect on patients with OVCF after PKP,which can effectively improve the effect of vertebral body correction and improve the function of injured vertebral body.
作者
彭金建
吴锦华
袁志峰
PENG Jinjian;WU Jinhua;YUAN Zhifeng(Department of Orthopedics,the First People′s Hospital of Jingdezhen,Jiangxi Province,Jingdezhen 333099,China)
出处
《临床合理用药》
2025年第15期18-21,共4页
Chinese Journal of Clinical Rational Drug Use
