摘要
目的探讨孕晚期B群链球菌(GBS)感染的危险因素。方法选取2023年1月至12月于北部战区总医院完成产检且最终分娩的4115例孕晚期孕妇,均为女性,年龄(32.27±3.86)岁,年龄范围为19~46岁。收集孕妇的基本信息、孕产信息及病史资料,检测孕妇的GBS感染情况,统计GBS感染孕妇及非GBS感染孕妇的不良结局。结果4115例孕晚期孕妇中,GBS感染217例,占比5.27%,非GBS感染3898例,占比94.73%。GBS感染孕妇高龄、妊娠期糖尿病(GDM)、妊娠期高血压及孕期阴道炎占比高于非GBS感染孕妇,差异有统计学意义(P<0.05)。多因素logistic回归分析结果显示,年龄≥35岁、存在GDM和存在孕期阴道炎为孕晚期生殖道GBS感染的独立危险因素(P<0.05)。GBS感染孕妇与非GBS感染孕妇妊娠期间不良结局发生率比较,差异无统计学意义(P>0.05);产后非GBS感染孕妇的新生儿的不良结局发生率低于感染GBS孕妇的新生儿,差异有统计学意义(P<0.05)。结论年龄≥35岁、存在孕期阴道炎及存在GDM为孕晚期GBS感染的独立危险因素。
Objective Exploring the risk factors of Group B Streptococcus(GBS)infection in late pregnancy.Methods A total of 4115 pregnant women admitted to the General Hospital of Northern Theater Command from January to December 2023 were selected,all of whom were female,aged(32.27±3.86)years old.ranging form 19 to 46 years old.Collect basic information,pregnancy and childbirth information,and medical history data of pregnant women,detect GBS infection status of pregnant women,and record adverse outcomes of GBS infected pregnant women,non GBS infected pregnant women.Results Among 4115 pregnant women in the late stage of pregnancy,there were 217 cases of GBS infection,accounting for 5.27%,and 3898 cases of non GBS infection,accounting for 94.73%.The proportion of older women,gestational diabetes(GDM),gestational hypertension and pregnancy vaginitis in GBS infected women were higher than that in non GBS infected women,with a statistically significant difference(P<0.05).The results of logistic multivariate analysis showed that age≥35 years old,presence of GDM,and vaginitis during pregnancy were independent risk factors for GBS infection in the late stage of pregnancy(P<0.05).There was no statistically significant difference in the incidence of adverse reactions during pregnancy between GBS infected and non GBS infected pregnant women(P>0.05);the incidence of adverse reactions in newborns of non GBS infected pregnant women after childbirth is lower than that of newborns of GBS infected pregnant women,and the difference was statistically significant(P<0.05).Conclusion Age≥35 years old,presence of vaginitis during pregnancy,and presence of GDM are independent risk factors for GBS infection in late pregnancy.
作者
李鸿飞
张苗
曲冬颖
孙静莉
洪岩
LI Hong-fei;ZHANG Miao;QU Dong-ying;SUN Jing-li;HONG Yan(Department of Laboratory,General Hospital of Northern Theater Command,Shenyang 110000,China)
出处
《创伤与急危重病医学》
2025年第3期185-188,194,共5页
Trauma and Critical Care Medicine
基金
辽宁省科学技术计划项目(2021JH2/10300095)。
关键词
B群链球菌
孕晚期
高危因素
妊娠结局
Group B Streptococcus infection
Late pregnancy
High risk factors
Pregnancy outcome
