摘要
Background and Objectives:The objective of this study was t o examine the effects of nutritional therapy in adult patients with severe burns.Methods and S tudy Design:Sixty adult patients with severe burns were en rolled.Data on nutritional intake through enteral nutrition(EN)or parenteral nutrition(PN)on days 7,14,21,and 28 post-injury were collected.Patients were divided into target and non-target groups according to whether their energy or protein intake reached the target.A ge,length of ventilation,and total bilirubin(TBIL),albumin(ALB),prealbumin(pALB),and C-reactive protein(CRP)concentrations of patients were recorded.Results:The per centage of protein targets with protein delivery was lower than that of energy target with energy delivery.The ra tio of PN protein to total protein was lower than that of PN energy to total energy on days 7,14,21,and 28(p<0.001,p<0.001,p=0.001,and p=0.003,respectively).Compared to the non-target group on day 21,the target group was younger,had lower TBIL on day 7,higher ALB and pALB on day 21,and lower CRP on day 14(p=0.025,p=0.021,p=0.028,p=0.029,and p=0.049,respectively).Multivariate logistic regression analysis showed that older age and longer ventilation were independent risk factors in patients who did not meet the nutri tional target on day 21(p=0.026 and p=0.043,respectively).Conclusions:The protein intake of adult patients with severe burns was low.Compared to the non-target group,the target group had better laboratory test results.Older age and longer ventilation were independent risk factors for patients not meeting the nutritional target.
基金
supported by the Wuhan Municipal Health Commission Scientific Research Project(grant number WG20B01)。