摘要
目的:分析血管内介入疗法在颈动脉狭窄患者中的应用效果。方法:选取2021年1月—2023年12月于河池市人民医院住院治疗的60例颈动脉狭窄患者作为研究对象,根据随机数字表法分为两组。对照组(n=30)采用内科保守疗法进行治疗,研究组(n=30)采用血管内介入疗法联合药物疗法进行治疗。比较两组病变血管血流情况、美国国立卫生研究院卒中量表(NIHSS)评分、简易智力状态检查量表(MMSE)评分、不良事件发生情况。结果:干预后两组病变血管收缩期峰流速、舒张末期流速均比干预前降低,且研究组低于对照组(P <0.05)。干预后两组NIHSS评分均比干预前降低,且研究组低于对照组(P <0.05)。干预后两组MMSE评分均比干预前升高,且研究组高于对照组(P <0.05)。两组不良事件发生率对比,差异无统计学意义(P> 0.05)。结论:对颈动脉狭窄患者进行血管内介入治疗可显著改善其病变血管的血流情况,提升其神经及认知功能,且安全性较高。
Objective:To analyze the application effect of endovascular interventional therapy in patients with carotid artery stenosis.Methods:Sixty patients with carotid artery stenosis hospitalized at Hechi People’s Hospital from January 2021 to December 2023 were selected as study subjects and divided into two groups using the random number table method.The control group(n=30)received medical conservative therapy,while the study group(n=30)underwent endovascular interventional therapy combined with pharmacotherapy.The blood flow status of the affected vessels,National Institutes of Health Stroke Scale(NIHSS)scores,Mini-Mental State Examination(MMSE)scores,and incidence of adverse events were compared between the two groups.Results:After intervention,the peak systolic velocity and end-diastolic velocity of the affected vessels in both groups decreased compared with those before intervention,with the study group exhibiting lower values than the control group(P<0.05).The NIHSS scores of both groups decreased post-intervention,with the study group showing lower scores than the control group(P<0.05).The MMSE scores of both groups increased post-intervention,with the study group demonstrating higher scores than the control group(P<0.05).There was no statistically significant difference in the incidence of adverse events between the two groups(P>0.05).Conclusion:Endovascular interventional therapy for carotid artery stenosis significantly improves blood flow in the affected vessels,enhances neurological and cognitive functions,and demonstrates a favorable safety profile.
作者
廖征吕
韩宗华
LIAO Zhenglv;HAN Zonghua(Hechi People's Hospital,Hechi 547000,China)
出处
《延边大学医学学报》
2025年第5期95-97,共3页
Journal of Medical Science Yanbian University
关键词
颈动脉狭窄
血管内介入疗法
血流情况
认知功能
carotid artery stenosis
endovascular interventional therapy
blood flow status
cognitive function