摘要
目的探讨合并白内障的原发性闭角型青光眼(primary angle-closure glaucoma,PACG)应用房角分离术联合超声乳化白内障吸除术治疗的效果。方法抽签法将我院2021年4月至2023年4月95例PACG合并白内障患者分2组,单一组47例开展超声乳化白内障吸除术,联合组48例联合房角分离术,对比两组临床疗效、眼压、中央前房深度、房角状态、角膜内皮细胞密度、角膜中心厚度、角膜内皮细胞平均面积,及并发症情况。结果3个月后,联合组总有效率93.75%(45/48)、中央前房深度(3.07±0.45)mm、角膜内皮细胞密度(2410.83±143.51)个/mm^(2)高于单一组的78.72%(37/47)、(2.48±0.36)mm、(2040.19±144.42)个/mm^(2),(χ^(2)=4.5397,P=0.0331;t=7.0474,12.5463,P=0.0000,0.0000);房角状态(宽房角36例,窄房角Ⅰ级5例,窄房角Ⅱ级7例)优于单一组(宽房角18例,窄房角Ⅰ级19例,窄房角Ⅱ级10例)(Z=3.1064,P=0.0019),角膜中心厚度(475.14±40.58)μm、眼压(15.29±1.77)mmHg、角膜内皮细胞平均面积(361.93±36.44)μm^(2)及并发症发生率2.08%(1/48)低于单一组(515.62±42.41)μm、(18.06±1.91)mmHg、(410.85±39.28)(μm^(2)、17.02%(8/47)),(t=4.7539,7.3339,6.2948,P=0.0000,0.0000,0.0000;χ^(2)=4.5597,P=0.0327)。结论PACG合并白内障患者开展超声乳化白内障吸除术联合房角分离术治疗能对患者房角状态进行有效改善,还可减少对角膜内皮的损伤,促进视力和眼压恢复,并发症较少。
Objective To investigate the effect of Goniosynechialysis with Phacoemulsification was performed in Primary angleclosure glaucoma(PACG)patients with cataract.Methods Ninety-five PACG patients with cataract in our hospital from April 2021 to April 2023 were divided into two groups by drawing lots.Forty-seven patients in the single group proceed phacoemulsification was performed,and 48 patients in the combined group combine with Goniosynechialysis.The clinical efficacy,intraocular pressure,central anterior chamber depth,anterior chamber angle status,corneal endothelial cell density,corneal central thickness,mean area of corneal endothelial cells,and complications.Results Three months later,The total effective rate 93.75%(45/48),central anterior chamber depth(3.07±0.45)mm,corneal endothelial cell density(2410.83±143.51)/mm^(2) in the combined group were higher than those in the single group 78.72%(37/47),(2.48±0.36)mm,(2040.19±144.42)/mm^(2),(χ^(2)=4.5397,P=0.0331;t=7.0474,12.5463,P=0.0000,0.0000);The anarior chamber anghe status(36 cases with wide anterior chamber angle,5 cases with narrow anterior chamber angle gradeⅠ,7 cases with narrow anterior chamber angle gradeⅡ)was better than that of single group(18 cases with wide anterior chamber angle,19 cases with narrow anterior chamber angle gradeⅠ,10 cases with narrow anterior chamber angle gradeⅡ)(Z=3.1064,P=0.0019).Corneal central thickness(475.14±40.58)μm,intraocular pressure(15.29±1.77)mmHg,mean area of corneal endothelial cells(361.93±36.44)μm^(2) and complication rate of 2.08%(1/48)were lower than those in single group(515.62±42.41)μm and(18.06±1.91)mmHg,(410.85±39.28)μm^(2),17.02%(8/47),(t=4.7539,7.3339,6.2948,P=0.0000,0.0000,0.0000;χ^(2)=4.5597,P=0.0327).Conclusion In PACG patients with cataract,Phacoemulsification was performed with Goniosynechialysis can effectively improve the anterior chamber angle status of patients,reduce the damage to corneal endothelia,promote the recovery of visual acuity and intraocular pressure,and have fewer complications.
作者
郝小英
陈梦平
申战省
李元元
HAO Xiaoying;CHEN Mengping;SHEN Zhansheng(Department of Ophthalmology,the Second People's Hospital of Zhengzhou City,Zhengzhou,450006,China)
出处
《实用防盲技术》
2025年第2期64-67,共4页
Journal of Practical Preventing Blind
