摘要
目的:对我院发生的1例复方氨基酸注射液(14AA-SF)致过敏反应的病因、临床治疗过程进行分析,为该药的临床安全合理应用提供参考。方法:使用药品不良反应关联性评价标准对该药进行评价,对既往复方氨基酸注射液致过敏反应的机制及病例报道进行回顾性分析。结果:复方氨基酸注射液(14AA-SF)引发过敏反应的关联性为“很可能”,患儿因不良反应发现及时,治疗措施有效,症状得到缓解。结论:临床在使用不含亚硫酸盐类抗氧化剂的复方氨基酸注射液(14AA-SF)时,也应注意过敏反应的防治。严格按照药品说明书规定控制滴速,在输注开始后特别是30 min内密切关注患者状态,提前制定治疗措施和抢救预案。
Objective:To analyze the etiology and clinical treatment process of allergic reaction induced by compound amino acid injection(14AA-SF)in our hospital,and to provide reference for the safe and rational clinical application.Methods:The drug was evaluated by using the correlation evaluation criteria for adverse drug reactions,and retrospective analysis was performed on mechanism and case reports of allergic reaction induced by previous compound amino acid injection.Results:The association of compound amino acid injection(14AA-SF)with allergic reaction was“very likely”.Due to the timely identification of adverse drug reactions and implementation of effective therapeutic interventions,the symptoms were successfully alleviated.Conclusion:When using compound amino acid injection(14AA-SF)without sulfite antioxidants in clinical practice,attention should be paid to the prevention and treatment of allergic reaction.The infusion rate should be strictly controlled according to the drug instructions,and patients’condition should be closely monitored after the start of infusion,especially within 30 min,with treatment measures and emergency protocols prepared in advance.
作者
岳山岚
邓毅
陈文文
Yue Shanlan;Deng Yi;Chen Wenwen(The Affiliated Women’s and Children’s Hospital,School of Medicine,University of Electronic Science and Technology of China,Chengdu Women’s and Children’s Central Hospital,Chengdu 611731,China)
出处
《儿科药学杂志》
2025年第6期44-46,共3页
Journal of Pediatric Pharmacy
