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胃癌患者术后化疗期衰弱管理的最佳证据总结

Summary of the best evidence for frailty management during postoperative chemotherapy in gastric cancer patients
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摘要 目的总结胃癌术后化疗期患者衰弱管理的最佳证据,为缓解患者衰弱提供参考。方法计算机检索UpToDate、BMJ Best Practice、国际指南协作网等计算机决策系统、PubMed、Embase、Web of Science等综合数据库及专业协会网站收录的关于胃癌术后化疗期患者衰弱管理相关的指南、专家共识、证据总结、系统评价、随机对照试验等,检索时限为建库至2024年9月15日。由2名研究人员独立筛选文献,并对纳入的文献进行质量评价,结合专业判断提取、汇总形成最佳证据。结果共纳入18篇文献,其中临床决策2篇,证据总结1篇,指南8篇,专家共识2篇,系统评价1篇,随机对照试验1篇,类实验研究2篇,观察性研究1篇。最佳证据包括衰弱的综合筛查、构建护理计划、术前预康复、营养干预、中医干预、运动干预、心理干预7个方面共34条证据。结论胃癌术后化疗期患者衰弱管理的最佳证据总结可为临床医护人员进行衰弱干预提供循证依据。 ObjectiveTo summarize the best evidence for frailty management in patients undergoing postoperative chemotherapy for gastric cancer,so as to provide reference for alleviating patient frailty.MethodsGuidelines,expert consensus,evidence summaries,systematic reviews,and randomized controlled trials and other articles on the frailty management of patients with postoperative chemotherapy for gastric cancer were electronically searched in computerized decision-making systems such as UpToDate,BMJ Best Practice,and Guidelines International Network,in comprehensive databases such as PubMed,Embase,and Web of Science,and in the websites of professional societies.The search period was from database establishment to September 15,2024.Two researchers independently screened the literature and evaluated the quality of the included literature,combining professional judgment to extract and summarize the best evidence.ResultsA total of 18 papers were included,including two clinical decisions,one evidence summary,eight guidelines,two expert consensus,one systematic review,one randomized controlled trial,two quasi-experimental studies,and one observational study.The best evidence included a total of 34 pieces in seven aspects of comprehensive screening,nursing plan construction,preoperative prehabilitation,nutritional interventions,Chinese medicine interventions,exercise interventions,and psychological interventions for frailty.ConclusionsThe summary of the best evidence for frailty management in patients undergoing postoperative chemotherapy for gastric cancer may provide an evidence-based basis for frailty interventions by clinical medical and staff.
作者 马纯雪 陈晓萱 张艳琼 陈晓静 林璋双 朱瑶瑶 林文君 夏丽敏 Ma Chunxue;Chen Xiaoxuan;Zhang Yanqiong;Chen Xiaojing;Lin Zhangshuang;Zhu Yaoyao;Lin Wenjun;Xia Limin(Ward 443,Gastrointestinal Surgery,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou 325000,China;Nursing Department,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou 325000,China)
出处 《中华现代护理杂志》 2025年第16期2160-2168,共9页 Chinese Journal of Modern Nursing
基金 2025年度浙江省医药卫生科技计划(2025713202) 2022年度省医药卫生厅科技项目(2022494566)。
关键词 胃肿瘤 化疗 衰弱 循证 证据总结 Stomach neoplasms Chemotherapy Frailty Evidence-based Evidence summary
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