摘要
Hepatocellular carcinoma(HCC)is one of the most common indications for liver transplantation(LT).With expanding criteria and increasing number of transplants,post-transplant recurrence of HCC remains an important cause for concern and portends a poor survival in these patients.Traditionally,HCC recurrence post-LT has been notoriously difficult to manage and their outcomes dismal.A better understanding of the tumour biology and its interplay with the immune system,combined with newer oncological interventions has allowed for improved survivals in these patients.A useful classification of HCC recurrence is where it is divided into oligo-recurrence and disseminated recurrence.This system helps strategize their multi-disciplinary management algorithm and prognosticate outcomes.We provide an overview of the factors which may predict recurrence and summarise the current evidence on the management of post-LT HCC recurrence.
