摘要
目的对黏弹性超声成像(VUI)评估代谢相关脂肪性肝病(MAFLD)进行方法学优化。方法选择行肝脏VUI的受试者140例,分为健康组55例和MAFLD组85例;MAFLD组根据MAFLD严重程度分为轻度组(40例)、中度组(25例)、重度组(20例)。分别在肝S3、S5、S6段各进行5次黏性系数(Vi)和频散系数(Disp)测量。使用组内相关系数(ICC)分析测量的一致性。比较各组间Vi和Disp。结果Vi和Disp在S5肝段均表现出最高ICC值,具有良好一致性。同组Vi和Disp测量1、2、3、4、5次间比较,差异均无统计学意义(P>0.05)。Vi值健康组和轻度组分别低于中度组和重度组,且中度组低于重度组(P<0.05)。Disp值健康组、轻度组、中度组均低于重度组(P<0.05)。结论为确保数据的准确性和可靠性,黏弹性超声成像评估肝脏时推荐在S5测量5次Vi、Disp,取平均值。Vi和Disp在健康组和不同严重程度MAFLD组之间具有差异。
Aim This study aims to optimize the methodology of viscoelastic ultrasound imaging(VUI)for assessing metabolic associated fatty liver disease(MAFLD).Methods A total of 140 subjects who underwent liver VUI were selected and divided into 55 cases in the healthy group and 85 cases in the MAFLD group;the MAFLD group was further categorized into mild(40 cases),moderate(25 cases),and severe(20 cases)groups according to the severity of MAFLD.Five viscosity coefficient(Vi)and dispersion coefficient(Disp)measurements were performed in each of the hepatic S3,S5,and S6 segments,respectively.The consistency of the measurements was analyzed using the intra-class correlation coefficient(ICC).Vi and Disp were compared between groups.Results Vi and Disp exhibited the highest ICC values in segment S5,demonstrating excellent consistency.No significant differences were observed among the five consecutive measurements of Vi and Disp within each group(P>0.05).Vi values in the healthy and mild MAFLD groups were significantly lower than those in the moderate and severe groups,with the moderate group showing lower values than the severe group(P<0.05).Disp values in the healthy,mild,and moderate groups were all lower than those in the severe group(P<0.05).Conclusion To ensure the accuracy and reliability of the data,viscoelastic ultrasonography evaluation of the liver is recommended to measure Vi and Disp five times at S5 to calculate the average value.Vi and Disp differ between the healthy group and different MAFLD groups.
作者
李建国
骆云皓
李蓉
杨腊梅
谭彦
谯朗
LI Jianguo;LUO Yunhao;LI Rong;YANG Lamei;TAN Yan;QIAO Lang(Department of Medical Ultrasound,the Third People's Hospital of Dazhou,Dachuan District People's Hospital of Dazhou,Dazhou 635000,Sichuan,China;Department of Ultrasound,Sichuan Integrative Medicine Hospital,Chengdu 610041,Sichuan,China;College of Medical and Life Sciences,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,Sichuan,China)
出处
《中南医学科学杂志》
2025年第3期431-434,438,共5页
Medical Science Journal of Central South China
基金
四川省科技厅科技计划项目(2024NSFSC0725)。
关键词
黏弹性超声成像
Vi
Disp
代谢相关脂肪性肝病
方法学
viscoelastic ultrasound imaging
Vi
Disp
metabolic associated fatty liver disease
methodology
