摘要
Badk ground:The role of cardiothoracic ratio(CTR)from the chest radiograph for assessmentof ventricular enlargement and function in rpaired tetralogy of Fallot(TOF)is conflicting.This study aimnedto determnine the associations between CTR and cardiac magnetic resonance(CMR)-derived ventricularvolumes and indices of ventricular function in adolescents and young adults with repaired TOF.Methods:The CTR and CMR findings,performed within 12 months of each other,were reviewed in 76 patients aged22.1±6.4 years.Associations between CTR and CMR parameters including right(RV)and left ventricular(LV)volumes and ejecticn fraction were determined.Diagnostic accuracies of CTR in identify ing moderateto severe RV or LV dilation were assessed by calculation of area under the receiver operator characteristiccurves(AUC),Results:Patients with normal CTR and those with increased CTR>0.5 had simnilar right andleft ventricular volumes,ejection fraction,and pulmonary regurgitant fraction(all p>0.05),There wereno significant oorrelations between CTR and RV end-diastolic(r=0.06,p=0.65)and end-systolic(r=0.06,=0.65)volumes,LV end-diastolic(=0.23,p=0.08)and end-systolic(r=0.18,p=0.16)volumes,and LV(r=—0.07,p=0.60)and RV(r<-0.01,p=0.97)ejection fraction.The CTR failed to distinguish betweenpatients with moderate to severe RV(AUC0.50)or LV(AUC 0.46)dilation from patients without ventriculardilation.Condlusions:The CTR based on the chest radiograph failed to reflect dilation or raduced ejectionfraction of either the right or the left ventricle in adolescents and young adults with repaired TOF.
