摘要
本文综述了主要几种接骨木属植物的传统药用价值及其化学成分、药理作用和质量标准的研究现状,旨在指出现有研究的不足;为今后的研究、开发和利用提供参考,为新药研发提供思路。接骨木属植物具有接骨续筋、祛风利湿、活血止痛等功效,其丰富的化学成分如酚类、萜类、糖及糖苷类、甾体类、生物碱类等赋予了其多种药理活性,如促进骨骼形成与保护、抗炎、镇痛、抗氧化、抗菌以及调节血压、血脂和血糖等。目前研究主要聚焦于化学成分分析和药理活性探索,但在作用机制阐明和质量标准建立方面尚需进一步深入研究。
This paper reviews the research status of the traditional medicinal value,chemical composition,pharmacological effects and quality standards of several main Sambucus L.plants,aiming to point out the existing research gaps,provide a reference for future research,development and utilization,and provide new ideas for new drug research and development.Sambucus L.plants have the effects of bone healing,dispelling wind and inducing dampness,invigorating blood circulation,relieving pain and so on.The rich chemical components such as phenols,terpenoids,sugars and glycosides,steroids,alkaloids,etc.give the plants a variety of pharmacological activities,such as promoting bone formation and protection,anti-inflammatory,analgesic,antioxidant,antibacterial effects and regulating blood pressure,blood lipids and blood glucose.At present,the research mainly focuses on chemical composition analysis and pharmacological activity exploration,but further research is needed to clarify the mechanism of action and establish quality standards.
作者
杨柳
赵晨曦
陈安欣
王东娜
王美华
李婷婷
YANG Liu;ZHAO Chenxi;CHEN Anxin;WANG Dongna;WANG Meihua;LI Tingting(College of Pharmacy,Dali University,Dali 671000,Yunnan Province,China;Department of Pharmacy,The People's Hospital of Xishuangbanna Dai Autonomous Prefecture,Jinghong 666100,Yunnan Province,China)
出处
《药学前沿》
2025年第5期859-867,共9页
China Pharmacist
基金
西双版纳州科技局项目(2024SWYY17)
云南省科技厅科技计划项目(202105AC160007)。
关键词
接骨木属
应用
化学成分
药理作用
质量标准
Sambucus L.
Application
Chemical constituents
Pharmacological effects
Quality standard