摘要
α-Trifluoromethyl ketones are a class of useful compounds with versatile applications.Their synthetic application via the transformation of the C—F bonds is of particular interest by allowing the synthesis of organic compounds with diverse structures.Herein,the advances in the research areas ofα-trifluoromethyl ketone synthesis and their defluorination reactions are reviewed.Discussion on the mechanisms of the typical reactions has also been provided,in hope of affording some guides to the chemistry ofα-trifluoromethyl ketones in the synthetic methods toward themselves and their derivatives.
α-三氟甲基酮是一类重要且功能多样的化合物.该类化合物通过碳-氟键官能化在有机合成中具有独特而有趣的应用,可用于合成具有结构多样的有机分子.综述了α-三氟甲基酮的合成及其脱氟官能化转化反应的研究进展.对于典型的反应,进行了反应机理方面的讨论,旨在为α-三氟甲基酮化学,包括它们本身以及由此衍生的产物合成提供参考.
出处
《有机化学》
北大核心
2025年第1期86-103,共18页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(No.22161022)资助项目
