摘要
应用黄曲霉毒素B_(1)(AFB_(1))致大鼠肝癌作用的短期实验模型,研究绿茶煎剂提取物(DEGT)、水溶性提取物(WEGT)和醇溶性提取物(EEGT)对AFB_(1)致肝癌作用的影响。结果发现,三种绿茶提取物对AFB_(1)诱发的肝癌前病变酶变灶均有显著的抑制效果,说明绿茶防癌作用的有效成分可溶于水和醇。为寻找绿茶防癌作用的主要有效成分提供了重要的线索。
Three kinds ofextractsof greentea(decoction extract of green tea,water extract of green tea and ethanol extract'of green tea)were tested for their effects on aflatoxin B_(1)(AFB_(1))-induced hepatocarcino-gonesis in rats.The rcsults revealed that all these three extracts of green tea possessed the remarkable inhibitory effects on the development of precancerous enzyme-altered hepatocellular foci.These results indi-cated that the main components of the green tea responsible for cancer prevention were all soluble in water and ethanol and thus providing an important clue for the search of thecffective components in green tea for cancer prevention.
出处
《中华预防医学杂志》
CSCD
北大核心
1991年第6期332-334,共3页
Chinese Journal of Preventive Medicine