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三维能量多普勒超声联合血清Fβ-hCG对单绒毛膜双羊膜囊双胎妊娠的诊断价值

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摘要 目的:探讨三维能量多普勒超声(3D–PDU)联合血清游离β亚基人绒毛膜促性腺激素(Fβ–hCG)检测在单绒毛膜双羊膜囊(MCDA)双胎妊娠胎盘血流中的诊断价值。方法:选取2023年2月至2023年8月在广州市花都区妇幼保健院进行产检的100例孕妇作为研究对象。其中,50例MCDA双胎妊娠孕妇作为观察组,50例健康单胎孕妇作为对照组。在同一指定的孕周中均进行3D–PDU检查和血清Fβ–hCG检测,对比两组的胎儿发育指标、胎盘血流指数及血清Fβ–hCG数值、3D–PDU联合血清Fβ–hCG的诊断价值。结果:观察组胎儿双顶径(BPD)、头围(HC)、腹围(AC)、股骨长(FL)均小于对照组(P<0.05);观察组胎盘血流指数中血管化指数(VI)、血流指数(FI)、血管化血流指数(VFI)及血清Fβ–hCG均高于对照组(P<0.05);3D–PDU联合血清Fβ–hCG诊断MCDA双胎妊娠的曲线下面积(AUC)为0.95(95%CI:0.91~0.98),灵敏度和特异度分别为(93.3%)和(90.0%),均高于单一检测方法(P<0.05)。结论:3D–PDU联合血清Fβ–hCG检测在MCDA双胎妊娠中的诊断价值较高。测定孕中期胎盘血流参数以及血清Fβ–hCG水平,为临床判断有无胎儿异常或并发症提供有力依据。
出处 《深圳中西医结合杂志》 2025年第1期94-96,113,共4页 Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
基金 广州市花都区医疗卫生一般科研专项项目(23-HDWS-064)。
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