摘要
目的 探究艾司氯胺酮联合丙泊酚静脉麻醉对宫腔镜手术患者的影响。方法 回顾性选取2022年1月—2023年12月扬中市人民医院行宫腔镜手术的80例患者的临床资料,根据麻醉方法不同分两组,各40例。研究组行艾司氯胺酮联合丙泊酚静脉麻醉,对照组行枸橼酸舒芬太尼联合丙泊酚静脉麻醉,对比两组的生命体征、苏醒质量、疼痛程度、不良反应发生率。结果 麻醉前,两组生命体征对比,差异无统计学意义(P>0.05)。在睫毛反应消失、扩张宫颈时、手术开始5 min,研究组生命体征数值高于对照组,差异均有统计学意义(P均<0.05)。研究组自主呼吸恢复时间为(2.65±0.78)min,呼之睁眼时间为(4.98±0.26)min,定向力恢复时间为(6.23±1.16)min,短于对照组的(4.36±1.29)min、(6.37±0.12)min和(8.54±1.39)min,差异均有统计学意义(t=7.174,30.700,8.070;P均<0.05)。术后10 min、术后30 min,研究组疼痛评分低于对照组,差异均有统计学意义(P均<0.05);术后1 d,两组疼痛评分对比,差异无统计学意义(P>0.05)。研究组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论 艾司氯胺酮联合丙泊酚静脉麻醉对宫腔镜手术患者具有显著优势,不仅可保持患者术中生命体征平稳,提高苏醒质量,还可降低疼痛程度和不良反应风险。
Objective To explore the effect of esketamine combined with propofol intravenous anesthesia on patients undergoing hysteroscopic surgery.Methods The clinical data of 80 patients who underwent hysteroscopic surgery in People´s Hospital of Yangzhong from January 2022 to December 2023 were retrospectively selected.They were divided into two groups according to different anesthesia methods,40 cases in each group.The study group was treated with esketamine combined with propofol intravenous anesthesia,and the control group was treated with sufentanil citrate combined with propofol intravenous anesthesia.The vital signs,recovery quality,pain degree and the incidence of adverse reactions of the two groups were compared.Results Before anesthesia,there was no significant difference in vital signs between the two groups(P>0.05).The vital signs of the study group were higher than those of the control group when the eyelash reaction disappeared,the cervix was dilated,and the operation began 5 min,the differences were statistically significant(all P<0.05).The spontaneous breathing recovery time of the study group was(2.65±0.78)min,the eye opening time was(4.98±0.26)min,and the directional force recovery time was(6.23±1.16)min,which were shorter than those of the control group(4.36±1.29)min,(6.37±0.12)min and(8.54±1.39)min,the differences were statistically significant(t=7.174,30.700,8.070;all P<0.05).At 10 min and 30 min after operation,the pain score of the study group were lower than those of the control group,and the differences were statistically significant(both P<0.05);at 1 d after operation,there was no significant difference in pain score between the two groups(P>0.05).The in‐cidence of adverse reactions in the study group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion Esketamine combined with propofol intravenous anesthesia has significant advantages for patients undergoing hysteroscopic surgery.It can not only maintain the stable vital signs of patients during operation,improve the quality of awakening,but also reduce the degree of pain and the risk of adverse reactions.
作者
孙志强
王超
金静芬
SUN Zhiqiang;WANG Chao;JIN Jingfen(Department of Anesthesiology,People´s Hospital of Yangzhong,Yangzhong,Jiangsu,212211,China)
出处
《中外医疗》
2025年第2期71-74,共4页
China & Foreign Medical Treatment
关键词
艾司氯胺酮
丙泊酚
宫腔镜手术
生命体征
苏醒质量
不良反应
Esketamine
Propofol
Hysteroscopic surgery
Vital signs
Quality of awakening
Adverse reactions
