摘要
2024年12月,欧洲肝脏研究协会在线发布了2024版《欧洲肝脏研究学会临床实践指南:肝细胞癌管理》的临床实践指南。相较于2018版指南,2024版指南在多方面进行了重要更新,包括基于个体风险评估的个性化监测策略、肝脏影像程序和诊断标准的标准化、复杂病例微创手术方式的应用、肝移植的整合作用、手术治疗和局部治疗及系统治疗之间的转换、放射治疗的定位,以及在疾病各阶段使用联合免疫治疗等。笔者就2024版指南中肝细胞癌治疗策略的更新内容进行系统解读,旨在为临床医师提供清晰的治疗决策参考。
In December 2024,the European Association for the Study of the Liver(EASL)released the 2024 edition of EASL clinical practice guidelines:management of hepatocellular carcinoma(HCC).Compared to the 2018 edition,the 2024 edition includes significant updates in several areas,such as personalized surveillance strategies based on individual risk assessment,standardization of liver imaging protocols and diagnostic criteria,the use of minimally invasive surgical approaches in complex cases,an updated approach to liver transplantation integration,transitions between surgery,locoregional,and systemic therapies,as well as the positioning of radiotherapy and the use of combination immunotherapy at various stages of the disease.The authors systematically interpret the main updates related to treatment strategies in the new guidelines,aiming to provide clinicians with clear decision-making references for treatment.
作者
杨钰泽
王明达
姚岚清
徐新飞
张平
沈锋
杨田
Yang Yuze;Wang Mingda;Yao Lanqing;Xu Xinfei;Zhang Ping;Shen Feng;Yang Tian(The First Ward of Hepatobiliary and Pancreatic Surgery,Department of General Surgery,First Hospital of Jilin University,Changchun 130031,China;Department of Hepatobiliary Surgery,Third Affiliated Hospital(Shanghai Eastern Hepatobiliary Surgery Hospital),Naval Medical University,Shanghai 200438,China)
出处
《中华消化外科杂志》
北大核心
2025年第2期198-205,共8页
Chinese Journal of Digestive Surgery
基金
国家自然科学基金(82425049,82273074,81972726)
上海市自然科学基金(22ZR1477900)
上海市优秀学术带头人计划项目(23XD1424900)
上海市卫生健康学科带头人项目(2022XD001)。
关键词
肝肿瘤
治疗策略
多学科诊疗
临床实践指南
解读
Liver neoplasms
Treatment strategies
Multidisciplinary team
Clinical practice guidelines
Interpretation
