摘要
目的分析同轴技术在超声引导下肝脏穿刺活检中的安全性和有效性。方法选取于我院行超声引导下肝脏穿刺活检的患者3358例,根据是否于超声引导下使用同轴技术分为同轴组2568例和非同轴组790例,比较两组穿刺成功率、取材满意率、标本数量、标本长度,以及并发症发生率、出血发生率及疼痛发生率的差异。进一步根据穿刺目标、活检针管径、凝血功能进行亚组分析,比较同轴组与非同轴组中各亚组并发症发生率和出血发生率的差异。结果两组穿刺成功率、取材满意率、标本数量、标本长度比较差异均无统计学意义。同轴组并发症发生率、出血发生率及疼痛发生率均低于非同轴组(6.39%vs.10.51%、0.74%vs.1.65%、5.33%vs.8.61%),差异均有统计学意义(均P<0.05)。亚组分析结果显示,同轴组中肝脏局灶性病变患者的并发症发生率和出血发生率均低于非同轴组,差异均有统计学意义(均P<0.05);同轴组使用18 G活检针患者的并发症发生率和出血发生率均低于非同轴组,差异均有统计学意义(均P<0.05);同轴组中凝血功能正常患者的并发症发生率低于非同轴组,凝血功能异常患者的出血发生率低于非同轴组,差异均有统计学意义(均P<0.05)。结论同轴技术在超声引导下肝脏穿刺活检中可获取足量组织用于病理诊断,且较非同轴技术具有更高的安全性。
Objective To analyze the safety and efficacy of the coaxial technique in ultrasound-guided liver biopsy.Methods A total of 3358 patients who underwent ultrasound-guided liver biopsy at our hospital were selected.Based on whether the coaxial technique was used,patients were divided into the coaxial group(2568 cases)and the non-coaxial group(790 cases).The success rate of puncture,sample satisfaction rate,number of specimens,specimen length,and incidence of complications,bleeding and pain were compared between the two groups.Subgroup analysis were further performed based on biopsy target,needle gauge,and coagulation function to compare the incidence of complications and bleeding between the coaxial and non-coaxial groups.Results There were no significant differences in success rate of puncture,sample satisfaction rate,number of specimens,specimen length between the two groups.However,the coaxial group had significantly lower rates of complications,bleeding,and pain compared to the non-coaxial group(6.39%vs.10.51%,0.74%vs.1.65%,5.33%vs.8.61%,all P<0.05).Subgroup analysis showed that the coaxial group had lower complication and bleeding rates in focal liver lesions compared to the non-coaxial group(all P<0.05),the coaxial group using 18 G needles had lower complication and bleeding rates compared to the non-coaxial group(all P<0.05),the coaxial group had lower complication rates in patients with normal coagulation function and lower bleeding rates in patients with abnormal coagulation function(both P<0.05).Conclusion The coaxial technique can obtain sufficient tissue for pathological diagnosis in ultrasound-guided liver biopsy and demonstrates higher safety compared to the non-coaxial technique.
作者
曾柯宇
王运涵
于波洋
卢强
ZENG Keyu;WANG Yunhan;YU Boyang;LU Qiang(Department of Ultrasound Medicine,West China Hospital of Sichuan University,Chengdu 610041,China)
出处
《临床超声医学杂志》
2025年第3期188-192,共5页
Journal of Clinical Ultrasound in Medicine
基金
四川省科技计划项目——青年科学基金项目(2025ZNSFSC1752)
四川大学华西医院院外横向科研协作项目(HX20230858)。
