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CT引导下同步穿刺活检联合射频消融术治疗肺结节效果及安全性分析

Effect and Safety of CT-guided Synchronous Puncture Biopsy Combined with Radiofrequency Ablation in the Treatment of Pulmonary Nodules
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摘要 目的探讨CT引导下同步穿刺活检联合射频消融术治疗肺结节的效果以及并发症发生情况。方法选择2023年1至10月收治的80例肺结节患者根据手术方法分为观察组和对照组各40例。对照组先行CT引导下穿刺活检术再接受射频消融术治疗,观察组行CT引导下同步穿刺活检、射频消融术。比较2组临床疗效、术后并发症及肺功能。结果80例经病理诊断均为恶性肺结节。2组总有效率比较差异无统计学意义(P>0.05)。观察组气胸、出血、胸腔积液、肺部感染总发生率[5.00%(2/40)]低于对照组[20.00%(8/40)],差异有统计学意义(P<0.05)。术后3个月,2组最大呼气流速峰值、用力肺活量均较术前降低,但观察组高于对照组(P<0.01)。结论CT引导下同步穿刺活检联合射频消融术治疗肺结节效果良好,且并发症较少,对肺功能的损伤相对较小。 Objective To investigate the effect and complications of computed tomography(CT)-guided synchronous puncture biopsy combined with radiofrequency ablation(RFA)in the treatment of pulmonary nodules.Methods In total,80 patients with pulmonary nodules admitted to the hospital from January to October 2023 were divided into the observation group(n=40)and the control group(n=40)according to surgical methods.The control group underwent CT-guided puncture biopsy followed by RFA,while the observation group underwent CT-guided synchronous puncture biopsy and RFA.The clinical efficacy,postoperative complications,and pulmonary function were compared between the two groups.Results All 80 patients were diagnosed as malignant pulmonary nodules through pathological examination.There was no significant difference in the total effective rate between the two groups(P>0.05).The total incidence of pneumothorax,bleeding,pleural effusion and pulmonary infection in the observation group was lower than that in the control group[5.00%(2/40)vs.20.00%(8/40)](P<0.05).At 3 months after surgery,peak expiratory flow rate and forced vital capacity were lower in both groups than those before operation,which,however,were higher in the observation group than in the control group(P<0.01).Conclusion CT-guided synchronous puncture biopsy combined with RFA is effective in the treatment of pulmonary nodules,with few complications and relatively less damage to pulmonary function.
作者 张阳 马保科 范敏 黄亚涛 李俊鹏 ZHANG Yang;MA Baoke;FAN Min;HUANG Yatao;LI Junpeng(Department of Thoracic Surgery,the First Hospital of Handan City,Handan,Hebei 056000,China)
出处 《临床误诊误治》 2025年第6期38-42,共5页 Clinical Misdiagnosis & Mistherapy
基金 邯郸市科学技术研究与发展计划项目(23422083293)。
关键词 肺结节 CT引导 射频消融 穿刺活检 气胸 胸腔积液 最大呼气流速峰值 用力肺活量 Pulmonary nodule CT-guided Radiofrequency ablation Needle biopsy Pneumothorax Pleural effusion Peak expiratory flow rate Forced vital capacity
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