摘要
[目的]分析2009―2019年江苏省肿瘤登记地区脑瘤发病趋势及年龄变化特征。[方法]选取江苏省16个质控合格肿瘤登记地区的2009―2019年脑瘤发病数据,计算不同性别和地区人群的脑瘤发病率、中国人口标化发病率(中标率)、平均发病年龄、标化年龄别发病构成以及平均年度变化百分比(average annual percentage change,AAPC)。[结果] 2009―2019年江苏省脑瘤发病率呈上升趋势(AAPC=4.12%,95%CI:3.31%~4.95%),女性(AAPC=5.79%,95%CI:4.44%~7.15%)上升幅度高于男性(AAPC=2.31%,95%CI:1.66%~2.97%),城市地区(AAPC=4.84%,95%CI:3.52%~6.18%)上升幅度高于农村地区(AAPC=3.04%,95%CI:2.12%~3.98%)。调整年龄构成后,中标率仍呈上升趋势(AAPC=2.14%,95%CI:1.27%~3.02%)。出生队列分析结果显示,江苏省相同年龄组内的脑瘤发病率整体随出生年份的后延而增加。平均发病年龄出现后移趋势,每年增加0.43岁(t=7.09,P<0.001),调整人口年龄结构后,每年增加0.20岁(t=3.33,P=0.009)。与2009年相比,2019年江苏省脑瘤在60岁及以上年龄组构成比上升,由2009年的35.79%上升至2019年的44.18%。[结论] 2009―2019年江苏省肿瘤登记地区脑瘤发病率呈上升趋势,平均发病年龄后移,未来需要进一步加强以人群为基础的肿瘤登记工作,并制定有针对性的防治策略,以逐步降低江苏省脑瘤疾病负担。
[Purpose]To analyze the trends of brain tumor incidence and age of onset in cancer registration areas of Jiangsu Province from 2009 to 2019.[Methods]The incidence data of brain tumors from 2009 to 2019 were obtained from 16 national cancer registration areas of Jiangsu Province.The crude incidence rate,age-standardized incidence rate by Chinese standard population(ASIRC),average age of onset,standardized age-specific incidence rate,and annual average percentage change(AAPC)by sexes and regions were calculated.[Results]The incidence rate of brain tumor in Jiangsu Province from 2009 to 2019 showed an increasing trend(AAPC=4.12%,95%CI:3.31%~4.95%),and the increase in female(AAPC=5.79%,95%CI:4.44%~7.15%)was higher than that in male(AAPC=2.31%,95%CI:1.66%~2.97%);and the increase in urban areas(AAPC=4.84%,95%CI:3.52%~6.18%)was higher than that in rural areas(AAPC=3.04%,95%CI:2.12%~3.98%).The ASIRC also showed an increasing trend(AAPC=2.14%,95%CI:1.27%~3.02%).Birth cohort analysis showed that within the same age group,the incidence rate of brain tumors increased with increasing birth years.The average age of onset for crude incidence showed a delaying trend of 0.43 years old per year(t=7.09,P<0.001);that for ASIRC was 0.20 years old per year(t=3.33,P=0.009).The proportion of patients in the age group of 60 years old and above increased from 35.79%in 2009 to 44.18%in 2019.[Conclusion]The incidence of brain tumor in cancer registration areas of Jiangsu Province showed an increasing trend from 2009 to 2019 with a delaying trend of average age of onset.
作者
刘德
张盼
乔程
李婷
陈培培
董宗美
周金意
陶然
缪伟刚
韩仁强
LIU De;ZHANG Pan;QIAO Cheng;LI Ting;CHEN Peipei;DONG Zongmei;ZHOU Jinyi;TAO Ran;MIAO Weigang;HAN Renqiang(Xuzhou Municipal Center for Disease Control and Prevention,Xuzhou 221000,China;Jiangsu Provincial Center for Disease Control and Prevention,Nanjing 210009,China)
出处
《中国肿瘤》
北大核心
2025年第2期116-124,共9页
China Cancer
基金
徐州市科学技术局项目(KC23228)
徐州市卫生健康委科技项目(XWKYHT20230015)。
关键词
脑瘤
发病率
发病年龄
趋势分析
江苏
brain tumor
incidence
age of onset
trend analysis
Jiangsu
