摘要
中药单体及其复方制剂治疗乳腺癌效果显著,具有多分子、多靶向、不良反应少等独特优势。红花多糖、别欧前胡素、穿心莲内酯、柴胡皂苷D等中药成分可通过调控PI3K/Akt、MAPK、Wnt、酪氨酸激酶/转录激活因子等信号通路抑制乳腺癌恶性进展。
TCM monomer and its compound preparation have significant effect in the treatment of breast cancer,with unique advantages of multi molecule,multi targeting,less adverse reactions,etc.TCM components such as Carthamus tinctorius polysaccharides,peimine,andrographolide,and Bupleurum saponin D can inhibit the malignant progression of breast cancer by modulating signaling pathways including PI3K/Akt,MAPK,Wnt,and JAK/STAT.
作者
王晓雅
焦方正
魏静
刘芳
潘艳芳
方艳
Wang Xiaoya;Jiao Fangzheng;Wei Jing;Liu Fang;Pan Yanfang;Fang Yan(School of Basic Medicine,Shaanxi University of Chinese Medicine,Xianyang 712046,China;Medical School of Yan'an University,Yan'an 716000,China;Department of Pathology,the Second Affiliated Hospital of Shaanxi University of Chinese Medicine,Xianyang 712046,China)
出处
《国际中医中药杂志》
2025年第1期137-141,共5页
International Journal of Traditional Chinese Medicine
基金
国家自然科学基金(82003806)。
关键词
癌
乳腺肿瘤
中医药
信号通路
研究进展
综述
Carcinoma
Breast cancer
TCM
Signaling pathway
Research progress
Review
