摘要
慢性阻塞性肺疾病(COPD)是一种最常见的慢性肺疾病,其主要特征是慢性不可逆性气道受阻。患者长期气流受限引起大脑供氧量减少,易引起大脑功能与结构的一系列改变。近年来很多MRI技术应用于COPD患者的研究。本文主要从静息态功能磁共振成像、基于体素的形态测量及弥散张量成像3个方面,对基于脑功能与结构成像技术在COPD中的研究进展进行综述。
Chronic obstructive pulmonary disease(COPD)is one of the most common chronic lung diseases,which is characterized by chronic irreversible airway obstruction.Chronic airflow restriction causes a decrease in oxygen supply to the brain,which inevitably leads to a series of changes in brain function and structure.In recent years,many magnetic resonance imaging(MRI)technology has been applied to explore the brain function and structure of COPD.Resting-state functional MRI,voxel-based morphometry,and diffusion tensor imaging are reviewed in this article to discuss the recent research progress of brain function and structure imaging study in COPD.
作者
于清扬
刘士远
YU Qingyang;LIU Shiyuan(Department of Radiology,The Second Affiliated Hospital of Naval Medical University(Second Military Medical University),Shanghai 200003,China)
出处
《海军军医大学学报》
北大核心
2025年第2期234-238,共5页
Academic Journal of Naval Medical University
基金
国家自然科学基金重点项目(81930049).
关键词
慢性阻塞性肺疾病
静息态功能磁共振成像
基于体素的形态测量
弥散张量成像
chronic obstructive pulmonary disease
resting-state functional magnetic resonance imaging
voxelbased morphometry
diffusion tensor imaging
