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表面增强拉曼光谱定量检测禽肉中抗生素的准确性与灵敏度评估

Evaluation of accuracy and sensitivity of surface-enhanced Raman spectroscopy for quantitative detection of antibiotics in poultry meat
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摘要 目的研究表面增强拉曼光谱(SERS)技术在禽肉中抗生素残留定量检测的应用,评估其在食品安全监测中的潜力。方法介绍SERS原理及增强因子计算,实验与模拟分析纳米颗粒形状和尺寸对SERS效应的影响。通过SERS检测不同浓度的抗生素残留,评估检测灵敏度和线性响应。结果SERS在0.8 nmol/L抗生素浓度下表现可靠,线性响应范围为0.1~1000 nmol/L,r^(2)为0.999,增强因子稳定在10~6量级。结论SERS技术具有高灵敏度和良好线性响应,适用于食品安全监测中的抗生素残留检测。 Objective To study the application of SERS technique in the quantitative detection of antibiotic residues in poultry meat and evaluate its potential in food safety monitoring.Methods The SERS principle and enhancement factor calculation were introduced,and the influence of the shape and size of nanoparticles on SERS effect was analyzed experimentally and simulated.Different concentrations of antibiotic residues were detected through SERS,and the detection sensitivity and linear response were evaluated.Results SERS was reliable at 0.8 nmol/L antibiotic concentration,the linear response range was 0.1~1000 nmol/L,the r^(2) was 0.999,and the enhancement factor was stable at 106.Conclusion SERS technology has high sensitivity and good linear response,which is suitable for the detection of antibiotic residues in food safety monitoring.
作者 朱秀焕 唐晓伟 董爱斌 韦伟 常晨阳 ZHU Xiu-Huan;TANG Xiao-Wei;DONG Ai-Bin;WEI Wei;CHANG Chen-Yang(Liaocheng Customs,Liaocheng 252000,China;Dezhou Customs,Dezhou 253000,China;Jinan Customs,Jinan 250000,China)
出处 《实验室检测》 2024年第11期158-160,共3页 Laboratory Testing
关键词 表面增强拉曼光谱 抗生素检测 禽肉残留 检测限 surface-enhanced Raman spectroscopy antibiotic detection poultry residue detection limit
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