摘要
目的 探究红细胞直接抗球蛋白试验(DAT)阳性原因和分型分布情况。方法 2021年7月至2202年12月期间,对来宾市人民医院重点用血科室的884例患者进行红细胞DAT,检测红细胞致敏情况,通过间接抗人球蛋白试验检测相关抗体,并查阅患者相关临床资料,对结果进行综合分析。结果 884例输血患者中,红细胞DAT阳性共122例,阳性率为13.80%。122例DAT阳性患者的分布情况为:消化血液内科占34.43%,重症医学科占27.05%,其次为肿瘤内科、小儿内科、妇产科及神经外科。122例DAT阳性患者的分型情况为:IgG型占62.30%,其次为IgG+C3d型、C3d型。结论 DAT阳性主要出现在消化血液内科和重症医学科,多见于血液病和感染性疾病患者中,类型以IgG型为主。
Objective:To explore the positive causes and distribution of erythrocyte direct antiglobulin test(DAT).Methods:From July 2021 to December 2002,884 patients in key blood departments of Laibin People's Hospital were subjected to red blood cell DAT to detect red blood cell sensitization,and the related antibodies were detected by indirect anti-human globulin test,and the relevant clinical data of patients were consulted,and the results were comprehensively analyzed.Results:Among 884 blood transfusion patients,122 were positive for red blood cell DAT,and the positive rate was 13.80%.The distribution of 122 DAT-positive patients was as follows:Gastroenterology Department accounted for 34.43%,Critical Care Department for 27.05%,followed by Oncology Department、Pediatric Department、Obstetrics and Gynecology Department and Neurosurgery Department.The typing of 122 patients with DAT positive was:IgG type accounted for 62.30%,followed by IgG+C3d type and C3d type.Conclusion:DAT positive mainly appears in gastroenterology and critical medicine,and it is more common in patients with hematological diseases and infectious diseases,with IgG as the main type.
作者
刘界明
韦庆成
罗培春
Liu Jieming;Wei Qingcheng;Luo Peichun(Blood Transfusion Department of Laibin People's Hospital,Laibin Guangxi 546199,China)
出处
《生命科学仪器》
2024年第5期169-172,共4页
Life Science Instruments
基金
药物性抗体与红细胞输注无效的相关性研究,广西壮族自治区卫生健康委员会自筹科研课题,项目编号:Z20210692
关键词
直接抗人球蛋白阳性
药物抗体
阳性分型
不规则抗体
Direct anti-human globulin positive
Drug antibody
Positive typing
Irregular antibody
