摘要
目的分析基于结构方程模型的静脉血栓栓塞症(VTE)患者抗凝延续性药学服务应用效果。方法选择2021年12月至2022年5月在深圳市龙岗中心医院确诊为VTE且经抗凝治疗后仍需口服抗凝药物的患者195例。对所有患者进行一般资料收集、药物治疗满意度、社会支持评定、抗凝药物知识及服药依从性调查,使用结构方程模型评价影响其抗凝药物服药依从性的因素,并验证模型的效能。结果VTE抗凝治疗患者的社会支持、药物治疗满意度、抗凝药物知识均对服药依从性具有正向影响。模型表现良好,GFI、AGFI、CFI、RMSEA均大于0.9,拟合度高。结论基于结构方程模型对VTE抗凝治疗患者延续性药学服务进行分析后发现,患者的社会支持、药物治疗满意度、抗凝药物知识均对其服药依从性具有显著影响。该模型显示出较高的可行性与有效性,有助于提高患者的治疗依从性与预期效果。
Objective:To analyze the application effect of anticoagulant continuous pharmaceutical care for patients with venous thromboembolism(VTE)based on structural equation model.Methods:195 patients who were diagnosed as VTE in Shenzhen Longgang Central Hospital from December 2021 to May 2022 and still needed oral anticoagulants after anticoagulant therapy were selected.The general data collection、drug treatment satisfaction、social support evaluation、anticoagulant knowledge and medication compliance were investigated in all patients,and the factors affecting their medication compliance were evaluated by structural equation model,and the effectiveness of the model was verified.Results:Social support,drug treatment satisfaction and anticoagulant knowledge of patients with VTE anticoagulation therapy have positive effects on drug compliance.The model performs well,and the GFI、AGFI、CFI and RMSEA are all greater than 0.9,and the fitting degree is high.Conclusion:Based on the structural equation model,the continuous pharmaceutical care of patients with VTE anticoagulation therapy was analyzed,and it was found that the patients'social support,drug treatment satisfaction and knowledge of anticoagulation drugs all had significant effects on their medication compliance.The model shows high feasibility and effectiveness,which is helpful to improve the treatment compliance and expected effect of patients.
作者
黄雪玉
刘素娟
吴柳清
Huang Xueyu;Liu Sujuan;Wu Liuqing(Pharmacy Department Shenzhen Longgang Central Hospital,Shenzhen Guangdong 518116,China)
出处
《生命科学仪器》
2024年第4期82-84,共3页
Life Science Instruments
基金
深圳市龙岗区医疗卫生科技计划项目,编号:LGWJ2021-(10)
关键词
静脉血栓栓塞症
结构方程模型
抗凝
延续性药学服务
服药依从性
Venous thromboembolism
Structural equation model
Anticoagulant
Continuous pharmaceutical care
Medication compliance
